ReviewInternational journal of dentistry2025
Analgesic Efficacy of Phytotherapeutic Agents in Dental Pain Management: A Systematic Review.
Review in International journal of dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Trial
- Bioactivity Assessment and In Silico Target Engagement ofFood science & nutrition · 2026Article
- Traditional Foods, Oral Microbiome, and Systemic Health: Molecular Pathways Linking Nutrition and Oral Disease Prevention.International journal of molecular sciences · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Toothache represents one of the most common reasons patients seek emergency dental care. While conventional analgesics remain the standard of care, phytotherapeutic agents offer potential alternatives with possibly fewer side effects. This systematic review evaluates the efficacy, safety, and clinical applications of plant-derived analgesic compounds in dentistry. Methods: A comprehensive search was conducted across electronic databases, including PubMed, Cochrane Library, Scopus, and Web of Science, for studies published between 15 Results: A total of 21 studies met the inclusion criteria. The phytotherapeutic agents demonstrating the strongest analgesic properties in dental applications include clove oil (eugenol), turmeric (curcumin), capsaicin from chili peppers, ginger powder, capsaicin, jidabokuippo, cannabis, propolis, Conclusion: Evidence supports the analgesic efficacy of several phytotherapeutic agents in toothache management, particularly eugenol, curcumin, and capsaicin. These offer promising alternatives or adjuncts to conventional analgesics, though standardization of preparations and larger RCTs are needed to establish optimal dosing regimens and long-term safety profiles.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.