Evidence map›Paper›PMID 41322685›Full record

ArticleAdvances in pharmacological and pharmaceutical sciences2025

Antileishmanial Activities of Methanol Extract and Solvent Fraction of

Amare Megersa, Aschalew Nardos, Tasisa Ketema, Serawit Deyno

Abstract read
In one paragraph

Article in Advances in pharmacological and pharmaceutical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Antileishmanial Activities of Methanol Extract and Solvent Fraction ofAdvances in pharmacological and pharmaceutical sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Amare MegersaDepartment of Pharmacy, Dilla University, Dilla, Ethiopia, du.edu.et.ORCID https://orcid.org/0009-0000-4062-8538
Aschalew NardosDepartment of Pharmacology, Hawassa University, Hawassa, Ethiopia, hu.edu.et.
Tasisa KetemaDepartment of Pharmacy, Ambo University, Ambo, Ethiopia, ambou.edu.et.ORCID https://orcid.org/0000-0002-8218-2252
Serawit DeynoDepartment of Pharmacology, Hawassa University, Hawassa, Ethiopia, hu.edu.et.ORCID https://orcid.org/0000-0001-7126-2815

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Leishmaniasis is a neglected tropical disease affecting 12 million people and risks the lives of 350 million people globally. However, it has limited therapeutic options. Objective: The aim of this study was to evaluate Methods: In vitro antileishmanial activity of crude extract of Result: The crude extract and its hexane, chloroform, and aqueous fractions exhibited antileishmanial activities, with IC Conclusion: The roots of the plant showed a promising antileishmanial activity that may provide a scientific justification for its use in traditional medicine. Further isolation, identification of active compounds, and establishment of the mechanism of action are warranted.

Indexed as

antiamastigoteantileishmanial activityantipromastigoteClematis simensis Fresen rootsL. aethiopicaL. donovani

Identifiers

PMID41322685
PMCPMC12657135

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.