Evidence map›Paper›PMID 41322609›Full record

ReviewACS omega2025

Carbon-Heteroatom Bond Formation via Photoinduced Decarboxylative Radical Coupling Reactions.

Danilo F C de Benedicto, Giovanna S Tâmega, Mateus O Costa, Marco A B Ferreira, Ricardo S Schwab

Abstract readReview
In one paragraph

Review in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Danilo F C de BenedictoLaboratory of Synthesis, Catalysis, and Modeling (SintCatMol), Chemistry Department, Federal University of São Carlos (UFSCar), Rodovia Washington Luís, km 235 - SP - 310, São Carlos, São Paulo 13565-905, Brazil.
Giovanna S TâmegaLaboratory of Synthesis, Catalysis, and Modeling (SintCatMol), Chemistry Department, Federal University of São Carlos (UFSCar), Rodovia Washington Luís, km 235 - SP - 310, São Carlos, São Paulo 13565-905, Brazil.
Mateus O CostaLaboratory of Synthesis, Catalysis, and Modeling (SintCatMol), Chemistry Department, Federal University of São Carlos (UFSCar), Rodovia Washington Luís, km 235 - SP - 310, São Carlos, São Paulo 13565-905, Brazil.ORCID https://orcid.org/0009-0001-7921-6300
Marco A B FerreiraLaboratory of Synthesis, Catalysis, and Modeling (SintCatMol), Chemistry Department, Federal University of São Carlos (UFSCar), Rodovia Washington Luís, km 235 - SP - 310, São Carlos, São Paulo 13565-905, Brazil.ORCID https://orcid.org/0000-0002-4954-6691
Ricardo S SchwabLaboratory of Synthesis, Catalysis, and Modeling (SintCatMol), Chemistry Department, Federal University of São Carlos (UFSCar), Rodovia Washington Luís, km 235 - SP - 310, São Carlos, São Paulo 13565-905, Brazil.ORCID https://orcid.org/0000-0001-8722-9403

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carboxylic acids are among the most widely used and versatile feedstock chemicals in organic synthesis. The generation of alkyl and aryl radicals through decarboxylation has emerged as a valuable strategy for the formation of both C-C and C-heteroatom bonds. Nevertheless, many reported protocols still rely on prior activation of carboxylic acids, which limits their cost-effectiveness and compromises environmental sustainability. This review aims to provide a comprehensive and critical overview of photoinduced decarboxylative coupling reactions employing free carboxylic acids as radical precursors for C-heteroatom bond formation. Particular emphasis is placed on the mechanistic insights underpinning these transformations, along with a discussion of their respective advantages, limitations, and potential for further development. By delineating the progress achieved thus far, we hope to stimulate continued innovation toward more sustainable, efficient, and broadly applicable decarboxylative coupling strategies.

Identifiers

PMID41322609
PMCPMC12658635

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.