Evidence map›Paper›PMID 41322607›Full record

ArticleACS omega2025

Regioselective Syntheses of Bis(indazolyl)methane Isomers: Controlling Kinetics and Thermodynamics via Tunable Non-Innocent Amines.

María Álvarez-Sánchez, Margarita Gómez, Carina Santos Hurtado, Jean Ngouné, Eleuterio Álvarez, Agustín Galindo, Claudio Pettinari

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

María Álvarez-SánchezInstituto de Investigaciones Químicas (IIQ), Spanish National Research Council (CSIC), University of Sevilla (US), Avda. Américo Vespucio 49, Isla de la Cartuja, 41092 Sevilla, Spain.
Margarita GómezInstituto de Investigaciones Químicas (IIQ), Spanish National Research Council (CSIC), University of Sevilla (US), Avda. Américo Vespucio 49, Isla de la Cartuja, 41092 Sevilla, Spain.
Carina Santos HurtadoInstituto de Investigaciones Químicas (IIQ), Spanish National Research Council (CSIC), University of Sevilla (US), Avda. Américo Vespucio 49, Isla de la Cartuja, 41092 Sevilla, Spain.
Jean NgounéChemistry Interdisciplinary Project (ChIP), School of Pharmacy, University of Camerino, Via Madonna delle Carceri, 62032 Camerino MC, Italy.
Eleuterio ÁlvarezInstituto de Investigaciones Químicas (IIQ), Spanish National Research Council (CSIC), University of Sevilla (US), Avda. Américo Vespucio 49, Isla de la Cartuja, 41092 Sevilla, Spain.ORCID https://orcid.org/0000-0002-8378-8459
Agustín GalindoDepartamento de Química Inorgánica, University of Sevilla (US), Aptdo. 1203, 41071 Sevilla, Spain.ORCID https://orcid.org/0000-0002-2772-9171
Claudio PettinariChemistry Interdisciplinary Project (ChIP), School of Pharmacy, University of Camerino, Via Madonna delle Carceri, 62032 Camerino MC, Italy.ORCID https://orcid.org/0000-0002-2547-7206

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The selective synthesis of regioisomers from ambident N-heterocycles remains a challenge in organic chemistry. We report a general and modular method for the regioselective syntheses of bis-(indazolyl)-methane isomers, in which the outcome is controlled by the nature of the base. Specifically, we employed structurally diverse amines as noninnocent bases, whose steric and electronic propertiesparticularly their p

Identifiers

PMID41322607
PMCPMC12658713

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.