Evidence map›Paper›PMID 41322465›Full record

ArticleCentral European journal of urology2025

In medio stat virtus: Exploring the potential of the pulsed thulium:YAG laser in the endoscopic management of upper tract urothelial carcinoma.

Silvia Proietti, Federico De Leonardis, Cristian Axel Hernandez Gaytan, Rebeca Escobar Monroy, Stefano Gisone, Riccardo Scalia, Franco Gaboardi, Guido Giusti

Abstract read
In one paragraph

Article in Central European journal of urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Silvia ProiettiDepartment of Urology, IRCCS San Raffaele Hospital, Milan, Italy.
Federico De LeonardisDepartment of Urology, IRCCS San Raffaele Hospital, Milan, Italy.
Cristian Axel Hernandez GaytanDepartment of Urology, IRCCS San Raffaele Hospital, Milan, Italy.
Rebeca Escobar MonroyDepartment of Urology, IRCCS San Raffaele Hospital, Milan, Italy.
Stefano GisoneDepartment of Urology, IRCCS San Raffaele Hospital, Milan, Italy.
Riccardo ScaliaDepartment of Urology, IRCCS San Raffaele Hospital, Milan, Italy.
Franco GaboardiDepartment of Urology, IRCCS San Raffaele Hospital, Milan, Italy.
Guido GiustiDepartment of Urology, IRCCS San Raffaele Hospital, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The pulsed thulium:YAG (p-Tm:YAG) laser has shown encouraging results in the management of stone disease and BPH; however, its application in the endoscopic management of upper tract urothelial carcinoma (UTUC) has not yet been clinically investigated. The aim of this study is to evaluate the effectiveness and safety of the p-Tm:YAG laser in the endoscopic management of UTUC. Material and methods: Retrospective data were collected from all patients who underwent endoscopic treatment for UTUC between January and April 2024. Eligible patients were those diagnosed with UTUC and deemed suitable for endoscopic management. Both low-grade and high-grade cases were included. All patients underwent a second-look procedure 2 months after the initial surgery, followed by endoscopic surveillance at 6 and 12 months postoperatively. The laser source used for tumor ablation and coagulation was the p-Tm:YAG laser. Results: A total of 20 patients were included in the study. Among them, 12 patients (60%) were included in the low-risk UTUC conservative treatment group, while 8 patients (40%) were categorized into the high-risk group. At the time of the second procedure, histopathological analysis revealed no evidence of tumor in 16 cases (80%), while a tumor was identified in 4 patients (20%). No intraoperative complications were recorded. Postoperatively, 10 out of 75 procedures (13.3%) were associated with Clavien-Dindo grade I-II complications. No major complications occurred. Conclusions: In short-term follow-up, the use of the p-Tm:YAG laser for endoscopic UTUC treatment has proven to be safe and effective.

Indexed as

conservative treatmentlaserpulsed thulium:YAGurothelial cancerUTUC

Identifiers

PMID41322465
PMCPMC12663822

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.