Evidence map›Paper›PMID 41322364›Full record

ArticleImaging neuroscience (Cambridge, Mass.)2025

Multimodal MRI reveals consistent basal ganglia and limbic system alterations in COVID-19 survivors.

Sapna S Mishra, Caterina A Pedersini, Rohit Misra, Preeti Yadav, Rakibul Hafiz, Bas Rokers, Bharat Biswal, Tapan K Gandhi

Abstract read
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In one paragraph

Article in Imaging neuroscience (Cambridge, Mass.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sapna S MishraDepartment of Electrical Engineering, Indian Institute of Technology Delhi, New Delhi, India.
Caterina A PedersiniPsychology, Division of Science, New York University Abu Dhabi, Abu Dhabi, United Arab Emirates.
Rohit MisraDepartment of Electrical Engineering, Indian Institute of Technology Delhi, New Delhi, India.
Preeti YadavDepartment of Electrical Engineering, Indian Institute of Technology Delhi, New Delhi, India.
Rakibul HafizDepartment of Biomedical Engineering, New Jersey Institute of Technology (NJIT), Newark, NJ, United States.
Bas RokersPsychology, Division of Science, New York University Abu Dhabi, Abu Dhabi, United Arab Emirates.
Bharat BiswalDepartment of Biomedical Engineering, New Jersey Institute of Technology (NJIT), Newark, NJ, United States.
Tapan K GandhiDepartment of Electrical Engineering, Indian Institute of Technology Delhi, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The long-term impact of COVID-19 on the brain is multifaceted, encompassing structural and functional disruptions. A cohesive theory of the underlying mechanisms of the Post-COVID Syndrome (PCS) remains unknown, primarily due to high variability in findings across independent studies. Here, we present a multimodal, cross-sectional MRI analysis of brain morphology (T1-MRI), tissue microstructure (diffusion-MRI), functional connectivity (functional-MRI), and cerebral blood flow (arterial spin labeling MRI) in COVID-recovered patients (CRPs, N=76) and healthy controls (HCs, N = 51). Although the global brain volumes did not differ between the two groups, CRPs showed focal atrophy in the right basal ganglia and limbic structures, along with cortical thinning in paralimbic regions (prefrontal cortex, insula) (

Indexed as

arterial spin labeling (ASL)diffusion-weighted MRI (dMRI)post-COVID syndrome (PCS)resting-state functional MRI (rs-fMRI)T1-weighted MRI

Identifiers

PMID41322364
PMCPMC12658774

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