A device for simultaneous neural recording and drug infusion in rodents.

Giovanni Barbera, Nicholas J Beacher, Da-Ting Lin

Abstract read

In one paragraph

Article in HardwareX, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Exercise as a Neurobiological Intervention: Utilizing NAc Circuitry to Combat Addiction.Addiction neuroscience · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Giovanni BarberaIntramural Research Program, National Institute On Drug Abuse, National Institutes of Health, Baltimore, MD 21224, USA.

Nicholas J BeacherDepartment of Psychology, Wittenberg University, Springfield, OH 455044, USA.

Da-Ting LinIntramural Research Program, National Institute On Drug Abuse, National Institutes of Health, Baltimore, MD 21224, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here we present and validate an open-source motorized swivel which allows simultaneous neural and behavioral recording from rodents during drug infusion experiments. Cable and drug line tangling represents a limiting factor for neural recordings in freely moving rodents. This limits the scope of experiments that can be carried out using currently available commutators. The proposed device offers a cost-effective solution to the problem of cable twisting and line tangling during experiments in freely moving rodents, enabling in vivo recordings for new experimental paradigms such as drug self-administration. Additionally, it requires minimal human supervision, simplifying the experimental design pipeline and facilitating scalability. To demonstrate the usefulness and functionality of the device, we performed in vivo miniscope imaging in rat during a drug self-administration task, showing individual neurons' response to drug seeking and consumption.

Indexed as

Drug infusionDrug self-administrationMiniscope commutatorMotorized commutatorNeural recording swivel

Identifiers

PMID41322361

DOI10.1016/j.ohx.2025.e00721

PMCPMC12663644

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.