Evidence map›Paper›PMID 41322321›Full record

ArticleJournal of conservative dentistry and endodontics2025

Histological evaluation of keratin and keratin with tricalcium phosphate as pulp capping agents: An animal study.

Selvam Suji, Nandhini Ambalavanan, Srilekha Jayakumar, Subramanian Dhanalakshmi, Muthukrishnan Sudharshana Ranjani, H Shalini

Abstract read
In one paragraph

Article in Journal of conservative dentistry and endodontics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Selvam SujiDepartment of Conservative Dentistry and Endodontics, Tamil Nadu Government Dental College and Hospital, Affiliated to the Tamil Nadu Dr. MGR Medical University, Chennai, Tamil Nadu, India.
Nandhini AmbalavananDepartment of Conservative Dentistry and Endodontics, Tamil Nadu Government Dental College and Hospital, Affiliated to the Tamil Nadu Dr. MGR Medical University, Chennai, Tamil Nadu, India.
Srilekha JayakumarDepartment of Conservative Dentistry and Endodontics, Chettinad Dental College and Research Institute, Kelambakkam, Affiliated to the Tamil Nadu Dr. MGR Medical University, Tamil Nadu, India.
Subramanian DhanalakshmiDepartment of Conservative Dentistry and Endodontics, Tamil Nadu Government Dental College and Hospital, Affiliated to the Tamil Nadu Dr. MGR Medical University, Chennai, Tamil Nadu, India.
Muthukrishnan Sudharshana RanjaniDepartment of Conservative Dentistry and Endodontics, Tamil Nadu Government Dental College and Hospital, Affiliated to the Tamil Nadu Dr. MGR Medical University, Chennai, Tamil Nadu, India.
H ShaliniDepartment of Conservative Dentistry and Endodontics, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, Chennai, Tamil Nadu, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Keratin is a naturally derived biomaterial that is biocompatible and can enhance pulp healing by a reparative response. There are limited studies on the effect of keratin on the repair and regeneration of dental tissue. The present study was conducted to histologically evaluate the pulpal response and calcific barrier formation after using keratin, tricalcium phosphate (TCP), and keratin + TCP as a direct pulp capping agent on goat teeth after a 90-day experimental period. Methodology: An in vivo animal study evaluated 36 teeth from 4 male goats (six lower incisors and Three lower premolars per goat) that were randomly divided into 3 groups ( Results: Histological evaluation revealed no significant difference in the distribution of samples with reference to inflammation ( Conclusion: Keratin + TCP may serve as an alternative for a pulp-capping agent due to their ability to induce a calcific barrier compared to keratin and TCP alone.

Indexed as

Keratinpulp-capping agenttricalcium phosphatevital pulp therapy

Identifiers

PMID41322321
PMCPMC12659893

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.