Evidence map›Paper›PMID 41322253›Full record

ArticlePCN reports : psychiatry and clinical neurosciences2025

Modified electroconvulsive therapy for severe malnutrition secondary to obsessive-compulsive disorder: A case report.

Masaya Miyazaki, Junko Yamamoto, Maiko Tsutsui, Emu Obara, Yuji Takamaru, Yoshihisa Sasagawa

Abstract read
In one paragraph

Article in PCN reports : psychiatry and clinical neurosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Reclaiming obsessionality: Beyond the obsessive-compulsive spectrum.PCN reports : psychiatry and clinical neurosciences · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Masaya MiyazakiDepartment of Psychiatry Otaru General Hospital Hokkaido Japan.ORCID https://orcid.org/0009-0005-2591-4444
Junko YamamotoDepartment of Psychiatry Otaru General Hospital Hokkaido Japan.
Maiko TsutsuiDepartment of Psychiatry Otaru General Hospital Hokkaido Japan.
Emu ObaraDepartment of Psychiatry Otaru General Hospital Hokkaido Japan.
Yuji TakamaruDepartment of Psychiatry Otaru General Hospital Hokkaido Japan.
Yoshihisa SasagawaDepartment of Psychiatry Otaru General Hospital Hokkaido Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Obsessive-compulsive disorder (OCD) is a chronic psychiatric condition marked by intrusive thoughts and repetitive behaviors. In rare cases, severe contamination or defecation fears lead to extreme dietary restriction and life-threatening malnutrition. Although a handful of cases have been reported, none describe the use of modified electroconvulsive therapy (mECT) in this setting. This report details the first known case of mECT for refractory OCD complicated by critical malnutrition. Case Presentation: A 54-year-old woman with longstanding contamination obsessions who had undergone prior trials of selective serotonin reuptake inhibitors (SSRIs) and exposure-and-response-prevention (ERP)-based cognitive-behavioral therapy (CBT) developed a rapid worsening of defecation fears following the death of her primary psychiatrist. To avoid perceived fecal contamination, she progressively restricted her diet, losing weight from 52 to 32.1 kg (body mass index [BMI] 13.1) and escalating to a Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) score of 39/40. Hospitalization for nutritional rehabilitation did not prevent further weight loss; therefore, mECT was initiated on Day 14 under general anesthesia, delivering 19 sessions in total. Symptoms improved rapidly: by the 13th session, her Y-BOCS score had fallen to 18/40, and she was able to consistently resume adequate oral intake. At the 10-month follow-up, she maintained a weight of 50.3 kg and a stable psychiatric status on paroxetine and CBT. Conclusion: mECT offers a rapid, effective intervention for treatment-refractory OCD complicated by critical malnutrition, achieving prompt symptom relief while simultaneously facilitating nutritional rehabilitation.

Indexed as

modified electroconvulsive therapyobsessive–compulsive disordersevere malnutritiontreatment‐resistant OCD

Identifiers

PMID41322253
PMCPMC12661587

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.