Evidence map›Paper›PMID 41322241›Full record

ArticleOpen forum infectious diseases2025

Skin and Soft Tissue Mucormycosis in Patients Receiving Bruton Tyrosine Kinase Inhibitors: Case Report and Literature Review.

Eduardo Aparicio-Minguijón, Nieves López-Muñoz, Jorge Boán, María Asunción Pérez-Jacoiste Asín, Javier de la Serna, Ana Pérez-Ayala, Ana Belén Enguita, Isabel Rodríguez-Goncer, Mario Fernández-Ruiz

Abstract readCase Reports
In one paragraph

Article in Open forum infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Eduardo Aparicio-MinguijónUnit of Infectious Diseases, Hospital Universitario "12 de Octubre," Instituto de Investigación Sanitaria Hospital "12 de Octubre,"  Madrid, Spain.ORCID https://orcid.org/0009-0007-1497-8770
Nieves López-MuñozDepartment of Hematology, Hospital Universitario "12 de Octubre," Instituto de Investigación Sanitaria Hospital "12 de Octubre,"  Madrid, Spain.ORCID https://orcid.org/0000-0003-0090-6673
Jorge BoánUnit of Infectious Diseases, Hospital Universitario "12 de Octubre," Instituto de Investigación Sanitaria Hospital "12 de Octubre,"  Madrid, Spain.ORCID https://orcid.org/0000-0003-2682-0819
María Asunción Pérez-Jacoiste AsínUnit of Infectious Diseases, Hospital Universitario "12 de Octubre," Instituto de Investigación Sanitaria Hospital "12 de Octubre,"  Madrid, Spain.ORCID https://orcid.org/0000-0003-1578-2909
Javier de la SernaDepartment of Hematology, Hospital Universitario "12 de Octubre," Instituto de Investigación Sanitaria Hospital "12 de Octubre,"  Madrid, Spain.ORCID https://orcid.org/0000-0003-3904-1101
Ana Pérez-AyalaDepartment of Medicine, School of Medicine, Universidad Complutense, Madrid, Spain.ORCID https://orcid.org/0000-0001-6426-6279
Ana Belén EnguitaDepartment of Pathology, Hospital Universitario "12 de Octubre," Instituto de Investigación Sanitaria Hospital "12 de Octubre,"  Madrid, Spain.
Isabel Rodríguez-GoncerUnit of Infectious Diseases, Hospital Universitario "12 de Octubre," Instituto de Investigación Sanitaria Hospital "12 de Octubre,"  Madrid, Spain.ORCID https://orcid.org/0000-0003-2150-5748
Mario Fernández-RuizUnit of Infectious Diseases, Hospital Universitario "12 de Octubre," Instituto de Investigación Sanitaria Hospital "12 de Octubre,"  Madrid, Spain.ORCID https://orcid.org/0000-0002-0315-8001

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bruton tyrosine kinase inhibitors (BTKis) have been associated with an increased risk of invasive fungal disease, with skin and soft tissue mucormycosis accounting for a minority of cases. We present a 72-year-old patient with chronic lymphocytic leukemia who developed necrotizing fasciitis and myositis due to

Indexed as

Bruton tyrosine kinase inhibitorchronic lymphocytic leukemiainfectionskin and soft tissue mucormycosiszanubrutinib

Identifiers

PMID41322241
PMCPMC12660008

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.