Clinical features analysis for complications in infants with late-onset Group B streptococcal sepsis: a retrospective case-control study.

Objective: To investigate the risk factors associated with complications in infants with late-onset Group B Streptococcal (GBS) sepsis, and to provide evidence for clinical intervention strategies. Methods: This study is a retrospective case-control study. The clinical data of 101 infants with late-onset GBS sepsis, diagnosed before 3 months of age were retrospectively analyzed. According to the presence or absence of complications, the infants were divided into the complication group and the non-complication group. Univariate and multivariate analyses were performed to explore the risk factors associated with the occurrence of complications in infants with late-onset GBS sepsis. Using ROC curves to evaluate the predictive efficacy of clinical variables. Results: A total of 101 cases of late-onset GBS sepsis met the inclusion criteria, including 41 in the non-complication group and 60 in the complication group. The gestational age in the complication group was significantly lower than that in the non-complication group ( Conclusion: High PELOD-2 score, high pSOFA score, high creatinine levels, and hypoalbuminemia independently predict complications in late-onset GBS sepsis infants, enabling early risk stratification and tailored treatment to improve outcomes.