Evidence map›Paper›PMID 41322228›Full record

ArticleFrontiers in medicine2025

Digit salvage therapy with integrated Chinese and Western medicine: report of case series.

Jiaming Cui, Hanbo Wang, Yanlong Yao, Junwei Zong, Ying Gong, Ran Sun, Mingzhi Song

Abstract readCase Reports
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jiaming Cui *School of Basic Medical Sciences, Shenzhen University, Shenzhen, Guangdong, China.
Hanbo Wang *Department of Biomedical Engineering, Stony Brook University, Stony Brook, New York, United States.
Yanlong Yao *Department of Burn and Wound, Dalian Fourth People's Hospital, Dalian, Liaoning, China.
Junwei ZongDepartment of Orthopaedics, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.
Ying GongDepartment of Orthopaedics, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.
Ran SunDepartment of Nursing, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.
Mingzhi SongInstitute of Translational Medicine, Jining Medical University, Rizhao, Shandong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Finger or toe trauma is a common orthopedic disease. However, the digit salvage treatment method for patients with severe tissue necrosis or infection is very limited. Methods: Five retrospective cases with typical lesions received our integrated traditional Chinese and Western medicine digit salvage therapy. These cases were with necrosis and defect or osteomyelitis. According to the patient's different lesion characteristics, we carried out the integrated treatment of traditional Chinese and Western medicine including nibbling debridement, negative pressure wound treatment (NPWT), moisture burn ointment (MEBO), rehabilitation exercise and common surgical techniques. Results: We considered that precarious alive tissue (PAT) in the residual tissue of the lesion area was very important, especially for promoting tissue regeneration and repairing defects. By nibbling debridement, PAT can be accurately identified. NPWT could protect wound, control infection and fully absorpt the effusion. MEBO was used for dressing changes. While rehabilitation exercise is very important to promote the function recovery. Additionally, bone drilling, skin-grafting and immobilization were also used in different cases. The affected finger or toe healed completely during 1.5-18 months. All patients restored the movement function of the adjacent joints in the lesion area. There was no recurrence of infection or complaint of pain. Conclusion: Therefore, traditional Chinese and Western medicine digit salvage therapy may offer an alternative to amputation in select cases. However, further research with larger sample sizes and controlled trials are still needed before wide application of this therapy.

Indexed as

digit salvage therapyintegrated Chinese and Western medicineMEBONPWTtissue necrosis defect

Identifiers

PMID41322228
PMCPMC12660232

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.