Evidence map›Paper›PMID 41321866›Full record

ReviewQuantitative plant biology2025

Small RNA, big defence: Early epigenetic responses to genetic invasion.

Seunghui Mun, Yang Jae Kang, Jungnam Cho

Abstract readReview
In one paragraph

Review in Quantitative plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Seunghui MunDurham University, UK.
Yang Jae KangGyeongsang National University, Republic of Korea.
Jungnam ChoDurham University, UK.ORCID https://orcid.org/0000-0002-4078-7763

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plants are under constant genetic siege. From viruses and bacteria to transposable elements within their genomes, cells must contend with foreign genetic material. Besides these natural threats, modern biotechnology adds complexity by introducing transgenes to plants. While the integration of such DNA can enhance genetic diversity and confer desirable traits, its foreign origin is typically recognised by the plant cell as a signal of invasion and therefore targeted by the repressive mechanisms. Epigenetic silencing is a central strategy and involves the methylation of DNA and histones. A critical trigger of this silencing is the generation of small interfering RNAs (siRNAs). Although the role of siRNAs in maintaining epigenetic silencing is well established, the initial steps that lead to their production remain incompletely understood. This review discusses the key discoveries on how plant cells recognise foreign nucleic acids and initiate epigenetic silencing, contributing to our broader understanding of genome integrity and defence.

Indexed as

epigenetic silencingNo-go RNA decayRNA-directed DNA methylationRNA quality controlsmall RNA

Identifiers

PMID41321866
PMCPMC12658303

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.