Evidence map›Paper›PMID 41321861›Full record

ArticleEuropean heart journal open2025

Wanling Liu, Maureen Dannenberg, Pascalle Mossel, Zeyu Cai, Inês Farinha Antunes, Jurgen Sijbesma, Chantal Kwizera, Lu Cao, Andries van der Meer, Robert Passier and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European heart journal open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Wanling LiuDepartment of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Hanzeplein 1, Groningen 9713 GZ, The Netherlands.
Maureen DannenbergApplied Stem Cell Technologies, Department of Bioengineering Technologies, TechMed Centre, University of Twente, Drienerlolaan 5, Enschede 7500 AE, The Netherlands.ORCID https://orcid.org/0009-0004-5896-992X
Pascalle MosselDepartment of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Hanzeplein 1, Groningen 9713 GZ, The Netherlands.
Zeyu CaiDepartment of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Hanzeplein 1, Groningen 9713 GZ, The Netherlands.
Inês Farinha AntunesDepartment of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Hanzeplein 1, Groningen 9713 GZ, The Netherlands.
Jurgen SijbesmaDepartment of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Hanzeplein 1, Groningen 9713 GZ, The Netherlands.
Chantal KwizeraDepartment of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Hanzeplein 1, Groningen 9713 GZ, The Netherlands.
Lu CaoLeiden Institute of Advanced Computer Science (LIACS), Universiteit Leiden, Niels Bohrweg 1, Leiden 2333 CA, The Netherlands.ORCID https://orcid.org/0000-0002-1847-068X
Andries van der MeerApplied Stem Cell Technologies, Department of Bioengineering Technologies, TechMed Centre, University of Twente, Drienerlolaan 5, Enschede 7500 AE, The Netherlands.ORCID https://orcid.org/0000-0002-8761-4077
Robert PassierApplied Stem Cell Technologies, Department of Bioengineering Technologies, TechMed Centre, University of Twente, Drienerlolaan 5, Enschede 7500 AE, The Netherlands.ORCID https://orcid.org/0000-0003-4312-9296
Riemer H J A SlartDepartment of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Hanzeplein 1, Groningen 9713 GZ, The Netherlands.ORCID https://orcid.org/0000-0002-5565-1164
Verena SchwachApplied Stem Cell Technologies, Department of Bioengineering Technologies, TechMed Centre, University of Twente, Drienerlolaan 5, Enschede 7500 AE, The Netherlands.ORCID https://orcid.org/0000-0003-1831-7412
Gert LuurtsemaDepartment of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Hanzeplein 1, Groningen 9713 GZ, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: P-glycoprotein (P-gp), an efflux transporter with diverse compound effects, is a vital part of cardiac function. To determine if the selective substrate tracer [ Methods and results: µ-EHTs were treated with the P-gp inhibitor Tariquidar (200 nM for 30 min) or the P-gp inducer Doxorubicin (1 µM for 24 h) and incubated with [ Conclusion: [

Indexed as

[18F]MC225Engineered heart tissuesHeart on a chipP-glycoproteinP-gpPositron emission tomography (PET)

Identifiers

PMID41321861
PMCPMC12662796

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.