Evidence map›Paper›PMID 41321774›Full record

ArticleRare tumors2025

Spontaneous regression of metastatic disease after palliative debulking surgery for heavily pre-treated extraskeletal myxoid chondrosarcoma: A case report.

Hailey Kathryn Carroll, Anna Keogh, Simon Barry, Aurelie Fabre, Gary O'Toole, John Crown, Deirdre O'Mahony, Kenneth Feeley, Asif Muneer, Richard M Bambury

Abstract read
In one paragraph

Article in Rare tumors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hailey Kathryn CarrollDepartment of Medical Oncology, Cork University Hospital, Cork, Ireland.ORCID https://orcid.org/0000-0002-3052-3975
Anna KeoghDepartment of Pathology, St Vincent's University Hospital, Dublin, Ireland.
Simon BarryDepartment of Medical Oncology, Cork University Hospital, Cork, Ireland.
Aurelie FabreDepartment of Pathology, St Vincent's University Hospital, Dublin, Ireland.
Gary O'TooleDepartment of Orthopaedic Surgery, St Vincent's University Hospital, Dublin, Ireland.
John CrownDepartment of Medical Oncology, St Vincent's Private Hospital, Dublin, Ireland.
Deirdre O'MahonyDepartment of Medical Oncology, Bon Secours Hospital, Cork, Ireland.
Kenneth FeeleyDepartment of Pathology, Bon Secours Hospital, Tralee, Ireland.
Asif MuneerMale Genital Cancer Centre, Department of Urology, University College London Hospitals NHS Foundation Trust, London, UK.
Richard M BamburyNational Institute for Health and Care Research (NIHR) Biomedical Research Centre, University College London Hospitals NHS Foundation Trust, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spontaneous regression of metastatic disease in the setting of advanced cancer is a poorly understood clinical phenomenon which occurs infrequently across all tumour types but exceptionally rarely in soft tissue sarcomas. Extraskeletal myxoid chondrosarcoma (EMC) is a rare subtype of soft tissue sarcoma that is poorly responsive to systemic treatment, providing limited options to patients with metastatic disease. We report spontaneous regression of lung metastases in a patient with EMC after re-resection of the primary tumour, which was performed with palliative intent for symptom control after multiple lines of systemic treatment. The patient has remained disease-free and is now more than 5 years post-surgery. To our knowledge, this is the first described case of spontaneous regression of metastatic disease following resection of a primary tumour in a patient with EMC.

Indexed as

debulking surgeryextraskeletal myxoid chondrosarcomalung metastasessarcomaspontaneous regression

Identifiers

PMID41321774
PMCPMC12660641

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.