Evidence map›Paper›PMID 41321762›Full record

ArticleBrain & spine2025

Prognostic factors for treatment success of conservative management and role for physiotherapy in radicular pain caused by a lumbar disc herniation: a systematic review.

Felix De Bruyn, Shaman Ambaliya, Bart Depreitere

Abstract read
In one paragraph

Article in Brain & spine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Felix De BruynNeurosurgery, University Hospitals Leuven, Leuven, Belgium.
Shaman AmbaliyaNeurosurgery, University Hospitals Leuven, Leuven, Belgium.
Bart DepreitereNeurosurgery, University Hospitals Leuven, Leuven, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Lumbar disc herniation is a frequent cause of radicular leg pain and has a pronounced impact on the quality of life. While guidelines discommend surgery in the acute phase of the condition, literature on conservative treatment is relatively scarce. In this systematic review, prognostic factors for success of conservative management are investigated as well as the effect of physiotherapy on leg pain. Methods: We searched PubMed, Embase, Cochrane Central Register of Controlled Trials (CENTRAL), Pedro, Web of Science, Scopus, CINAHL, ICTRP, and Clinicaltrials.gov from commencement to September 2022. Following screening 22 reports were included in the analysis and assessed for risk of bias by using the RoB 2 tool for randomized trials and the ROBINS-I tool for prospective cohort studies. Results: Fifteen papers with moderate to high risk of bias reported on prognostic factors for treatment success following nonsurgical management. Extruded disc morphology was associated with better outcomes in two articles. Severe baseline symptoms and receiving workers compensation were associated with worse outcomes in three and two studies, respectively. Physiotherapy reportedly had a beneficial effect on radicular leg pain in 5 out of 7 studies with low to moderate risk of bias. Conclusion: Certain physiotherapy actions seem to have value with respect to the relief of radicular symptoms in the conservative management of LDH with radicular pain. Severe baseline symptoms seems to be a risk factor for poor outcome after conservative management. There is a need for high-quality evidence on non-surgical treatments to match the literature on surgical treatment.

Indexed as

Conservative managementLumbar disc herniationPhysiotherapyPrognosisRadicular leg pain

Identifiers

PMID41321762
PMCPMC12657478

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.