Evidence map›Paper›PMID 41321573›Full record

ReviewFrontiers in veterinary science2025

Innovative lipid delivery systems in ruminant diets: the role of spray drying.

Thâmilla Thalline Batista de Oliveira, Thalia Catherine Sacramento Ferreira, Pedro Paulo Lordelo Guimaraes Tavares, Paulo Romano Cruz Correia, Cláudio Vaz Di Mambro Ribeiro, Carolina Oliveira de Souza

Abstract readReview
In one paragraph

Review in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Thâmilla Thalline Batista de OliveiraPostgraduate Program in Food Science, Faculty of Pharmacy, Federal University of Bahia, Salvador, Brazil.
Thalia Catherine Sacramento FerreiraPostgraduate Program in Food Science, Faculty of Pharmacy, Federal University of Bahia, Salvador, Brazil.
Pedro Paulo Lordelo Guimaraes TavaresPostgraduate Program in Food Science, Faculty of Pharmacy, Federal University of Bahia, Salvador, Brazil.
Paulo Romano Cruz CorreiaPostgraduate Program in Food Science, Faculty of Pharmacy, Federal University of Bahia, Salvador, Brazil.
Cláudio Vaz Di Mambro RibeiroSchool of Veterinary Medicine and Animal Science, Federal University of Bahia, Salvador, Brazil.
Carolina Oliveira de SouzaPostgraduate Program in Food Science, Faculty of Pharmacy, Federal University of Bahia, Salvador, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ruminant nutrition faces multifactorial challenges, including genetic limitations, inadequate management practices, and biochemical and physiological constraints within the ruminal environment, which compromise nutrient utilization, animal productivity, and the environmental sustainability of production systems. One of the main bottlenecks is microbial biohydrogenation of lipids, which reduces the energy efficiency of diets and the bioavailability of essential fatty acids in ruminants. Spray-drying-based microencapsulation technology has been proposed as a strategy to protect lipids and bioactive compounds. However, comprehensive mechanistic reviews integrating scientific evidence, technological development, and zootechnical applicability are still scarce. This systematic review aims to map the landscape of scientific literature and technological records regarding the use of microencapsulated lipids and tannins in ruminant feeding, with an emphasis on spray-drying as the primary microencapsulation technique. The methodology involved bibliometric and technological analyses using The Lens database, covering publications and patents from 2015 to 2025. A total of 1,190 patents and 163 scientific articles on fatty acid microencapsulation were identified, highlighting efforts to improve thermal and oxidative stability, control ruminal release, and increase the dietary energy efficiency. Regarding tannins, 161 patents and 29 studies emphasized their role as co-microencapsulants with antioxidant, antimicrobial, and fermentation-modulating properties. A scarcity of applied studies in tropical areas was observed, along with a geographic mismatch between areas of high technological output, such as Europe, and major ruminant-producing countries, such as Brazil and India, highlighting the need for regionally adapted innovation. The mapped landscape underscores the strategic and multidimensional potential of microencapsulation technologies to mitigate nutritional losses, reduce enteric emissions, and promote efficient livestock systems. This review provides a critical and updated analysis of the trends, barriers, and opportunities, offering insights into the pathways for sustainable innovation in ruminant nutrition. These findings underscore the importance of aligning scientific advances with practical solutions in animal production.

Indexed as

animal supplementationlipidsmicroencapsulationruminantstannins

Identifiers

PMID41321573
PMCPMC12662176

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.