Evidence map›Paper›PMID 41321513›Full record

ArticleAnimal nutrition (Zhongguo xu mu shou yi xue hui)2025

Dose-dependent inhibitory effects of an investigational feed additive containing bromoform on methane emissions from cattle fed fresh pasture.

Xuezhao Sun, Fiona Matiya, Pablo S Alvarez-Hess, Katherine Lowe, Silke Jacques, Martin J Auldist, David Pacheco

Abstract read
In one paragraph

Article in Animal nutrition (Zhongguo xu mu shou yi xue hui), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xuezhao SunAgResearch Group, New Zealand Institute for Bioeconomy Science Limited, Grasslands Research Centre, Palmerston North 4410, New Zealand.
Fiona MatiyaAgResearch Group, New Zealand Institute for Bioeconomy Science Limited, Grasslands Research Centre, Palmerston North 4410, New Zealand.
Pablo S Alvarez-HessRumin8 Pty Ltd., West Perth 6005, WA, Australia.
Katherine LoweAgResearch Group, New Zealand Institute for Bioeconomy Science Limited, Grasslands Research Centre, Palmerston North 4410, New Zealand.
Silke JacquesRumin8 Pty Ltd., West Perth 6005, WA, Australia.
Martin J AuldistRumin8 Pty Ltd., West Perth 6005, WA, Australia.
David PachecoAgResearch Group, New Zealand Institute for Bioeconomy Science Limited, Grasslands Research Centre, Palmerston North 4410, New Zealand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bromoform, a bioactive compound in certain seaweeds, has gained attention for its methane-mitigating effects in ruminants. Research is underway to use synthetic bromoform as an alternative for providing consistent and predictable dosing of the bioactive compound, but its inherent volatility and liquid form limit its application. To address these challenges, an investigational feed additive (IFA) in the form of a powder containing synthetic bromoform has been developed by Rumin8 Pty Ltd., West Perth, WA, Australia. The objective of this study was to evaluate the effect of the Rumin8 IFA on methane emissions from cattle fed fresh pasture. Sixteen 18-month-old Hereford × Friesian heifers (427 ± 11 kg; mean ± SD) were stratified by weight and randomly allocated to control and treatment groups using a randomised block design. Treatments included IFA doses at 100, 300, or 500 mg/d of bromoform per heifer, plus a placebo control. The heifers were fed fresh pasture twice daily with a total feed allowance set at a level of 1.6 to 1.8 times their maintenance energy requirements with 800 g of dried distiller's grain pellets containing treatments or placebo before each meal. After 16 d, the heifers' methane emissions were measured in open-circuit respiration chambers for 48 h. The results showed that pasture-fed heifers produced less methane when treated with the bromoform-containing IFA at every dose level (

Indexed as

CattleHydrogenMethanePastureSynthetic bromoformTissue residue

Identifiers

PMID41321513
PMCPMC12663497

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.