Evidence map›Paper›PMID 41321367›Full record

ArticleBMJ public health2025

COVID-19 immunisation among individuals with opioid use disorder in Ontario: a population-based cohort study.

Melina Hanna, Anna Maria Subic, Alison L Park, Fangyun Wu, Douglas M Campbell, Pamela Leece, Laurie Morrison, Janet Parsons, Kate Sellen, Carol Strike and 2 more

Abstract read
In one paragraph

Article in BMJ public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Melina HannaUniversity of Toronto Temerty Faculty of Medicine, Toronto, Ontario, Canada.
Anna Maria SubicUniversity of Toronto Dalla Lana School of Public Health, Toronto, Ontario, Canada.
Alison L ParkICES, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0001-5369-7639
Fangyun WuICES, Toronto, Ontario, Canada.
Douglas M CampbellLi Ka Shing Knowledge Institute, Unity Health Toronto, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0001-7046-0959
Pamela LeecePublic Health Ontario, Toronto, Ontario, Canada.
Laurie MorrisonDivision of Emergency Medicine, Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
Janet ParsonsLi Ka Shing Knowledge Institute, Unity Health Toronto, Toronto, Ontario, Canada.
Kate SellenDepartment of Systems Design, Faculty of Engineering, University of Waterloo, Waterloo, Ontario, Canada.
Carol StrikeUniversity of Toronto Dalla Lana School of Public Health, Toronto, Ontario, Canada.
Tara GomesICES, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0002-1468-1965
Aaron M OrkinUniversity of Toronto Dalla Lana School of Public Health, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0002-1111-8720

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The COVID-19 pandemic exacerbated health inequities, particularly among individuals with opioid use disorder (OUD). Disparities in vaccine uptake among people with OUD remain poorly understood. This study assessed COVID-19 immunisation rates among individuals with OUD compared with the general population in Ontario, Canada. Methods: This population-based retrospective cohort study used linked administrative health data to compare COVID-19 vaccination rates between individuals diagnosed with OUD and a 10% random sample of individuals without OUD. Ontario residents aged >15 years with continuous healthcare coverage as of the censor date, 16 March 2020, were included. Inverse Probability of Treatment Weighting (IPTW) was applied to balance confounders, and Cox proportional hazards models estimated adjusted HRs (aHRs) for receiving two and three or more vaccine doses. Results: The cohort included 105 733 individuals with OUD and 1 185 993 without OUD. Individuals with OUD had a lower hazard of receiving two vaccine doses (aHR: 0.75, 95% CI 0.73 to 0.76) and three or more doses (aHR: 0.69, 95% CI 0.67 to 0.70). The rate of two-dose and three-dose vaccination was also lower among those with OUD (115.3 vs 149.0 per 100 000 person-years and 44.7 vs 77.5 per 100 000 person-years). Conclusion: Individuals with OUD had lower COVID-19 vaccination rates, suggesting barriers to access and uptake. Addressing these disparities through targeted interventions is crucial for equitable public health responses.

Indexed as

COVID-19EpidemiologyPublic HealthSARS-CoV-2Vaccination

Identifiers

PMID41321367
PMCPMC12658482

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.