Evidence map›Paper›PMID 41321355›Full record

ArticleTrauma case reports2025

Masquelet technique combined with Ilizarov external fixation for the management of large femoral defects: A neglected technique.

Ioannis S Vasios, Konstantinos G Makiev, Marios Tryfonidis, Efthymios Iliopoulos, Paraskevas Georgoulas, Konstantinos Tilkeridis

Abstract readCase Reports
In one paragraph

Article in Trauma case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. [Advances on limb reconstruction technology for bone infection].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ioannis S VasiosAcademic Orthopaedics Department, University General Hospital of Alexandroupolis, Democritus University of Thrace (DUTh), Alexandroupolis, Greece.
Konstantinos G MakievAcademic Orthopaedics Department, University General Hospital of Alexandroupolis, Democritus University of Thrace (DUTh), Alexandroupolis, Greece.
Marios TryfonidisClinical Professor in Trauma & Orthopaedics, European University of Cyprus, Cyprus.
Efthymios IliopoulosAcademic Orthopaedics Department, University General Hospital of Alexandroupolis, Democritus University of Thrace (DUTh), Alexandroupolis, Greece.
Paraskevas GeorgoulasAcademic Orthopaedics Department, University General Hospital of Alexandroupolis, Democritus University of Thrace (DUTh), Alexandroupolis, Greece.
Konstantinos TilkeridisAcademic Orthopaedics Department, University General Hospital of Alexandroupolis, Democritus University of Thrace (DUTh), Alexandroupolis, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Large segmental femoral bone defects resulting from severe trauma, infection, or tumor resection present significant surgical challenges. Traditional methods like the Ilizarov bone transport technique and Masquelet technique are effective but have limitations. This study reports two cases of post-traumatic femoral bone defects successfully managed using a combination of the Masquelet technique and Ilizarov external fixation. The Masquelet technique, a two-stage process, involves the use of polymethyl methacrylate (PMMA) cement to induce membrane formation, followed by bone grafting at the second stage. The Ilizarov external fixator, known for its stability and versatility, was used to provide more rigid fixation than the monolateral device and to help prevent complications such as infection and nonunion. In both cases, the patients sustained open, high-energy femoral fractures with extensive bone loss and associated soft tissue defects. The Masquelet technique was used to manage the bone defects and the Ilizarov external fixator was employed to ensure stability, allow early mobilization and provide the option of bone transport if necessary. Both patients achieved fracture union with satisfactory functional outcomes. The combination of these techniques effectively addresses the biological and mechanical challenges of large femoral defects, offering a promising solution when internal fixation is not feasible. This approach can be considered a valuable addition to the treatment armamentarium for complex femoral fractures, particularly in cases with infection risk or severe bone loss.

Indexed as

Bone graftingFemoral bone defectsIlizarov external fixationInduced membrane techniqueMasquelet technique

Identifiers

PMID41321355
PMCPMC12661111

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.