Evidence map›Paper›PMID 41320962›Full record

ArticleThe Annals of otology, rhinology, and laryngology2026

Observation of Laryngeal Postures via High-Speed Videoendoscopy in Adductor Laryngeal Dystonia.

Katherine L Marks, Jenny Vojtech, Manuel E Díaz Cádiz, Laura E Toles, Taylor F Feaster, Andrew Wrede, Maanya Baranwal, Anastasia Haubrich, Misora Ito, Sophie Li and 16 more

Abstract read
In one paragraph

Article in The Annals of otology, rhinology, and laryngology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Katherine L MarksDepartment of Speech, Language, and Hearing Sciences, Boston University, MA, USA.ORCID 0000-0001-5483-3794
Jenny VojtechDepartment of Speech, Language, and Hearing Sciences, Boston University, MA, USA.
Manuel E Díaz CádizDepartment of Speech, Language, and Hearing Sciences, Boston University, MA, USA.
Laura E TolesDepartment of Otolaryngology-Head and Neck Surgery, University of Texas Southwestern Medical Center, Dallas, USA.ORCID 0000-0002-2665-3283
Taylor F FeasterDepartment of Speech, Language, and Hearing Sciences, Boston University, MA, USA.
Andrew WredeDepartment of Speech, Language, and Hearing Sciences, Boston University, MA, USA.
Maanya BaranwalDepartment of Speech, Language, and Hearing Sciences, Boston University, MA, USA.
Anastasia HaubrichDepartment of Speech, Language, and Hearing Sciences, Boston University, MA, USA.
Misora ItoDepartment of Speech, Language, and Hearing Sciences, Boston University, MA, USA.
Sophie LiDepartment of Speech, Language, and Hearing Sciences, Boston University, MA, USA.
Bonnie LittleDepartment of Speech, Language, and Hearing Sciences, Boston University, MA, USA.
Samantha LonerganDepartment of Speech, Language, and Hearing Sciences, Boston University, MA, USA.
Franklin PhanDepartment of Speech, Language, and Hearing Sciences, Boston University, MA, USA.
Giavanna SiracusanoDepartment of Speech, Language, and Hearing Sciences, Boston University, MA, USA.
Alex EstradaDepartment of Speech, Language, and Hearing Sciences, Boston University, MA, USA.
Jose M RojasDepartment of Speech, Language, and Hearing Sciences, Boston University, MA, USA.
Daniel P BuckleyDepartment of Speech, Language, and Hearing Sciences, Boston University, MA, USA.
Cara L SauderDepartment of Speech and Hearing Sciences, University of Washington, Seattle, USA.ORCID 0000-0001-9218-3737
Andrew KeltzDepartment of Otolaryngology Surgery, Yale School of Medicine, Greenwich, CT, USA.
Michael LernerDepartment of Otolaryngology Surgery, Yale School of Medicine, Greenwich, CT, USA.ORCID 0000-0002-8715-4533
Pavan MallurDepartment of Otolaryngology, Beth Israel Deaconess Medical Center, Boston, MA, USA.ORCID 0000-0001-8086-0534
Gregory GrilloneDepartment of Otolaryngology-Head and Neck Surgery, Boston University School of Medicine, MA, USA.
Pieter NoordzijDepartment of Otolaryngology-Head and Neck Surgery, Boston University School of Medicine, MA, USA.
Lauren F TracyDepartment of Otolaryngology-Head and Neck Surgery, Boston University School of Medicine, MA, USA.
Ted MauDepartment of Otolaryngology-Head and Neck Surgery, University of Texas Southwestern Medical Center, Dallas, USA.ORCID 0000-0002-1804-6707
Cara E SteppDepartment of Speech, Language, and Hearing Sciences, Boston University, MA, USA.ORCID 0000-0002-8045-252X

Funding

Objective Measures for Clinical Assessment of Voice DisordersR01DC015570 · NIDCD · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI STEPP, CARA E. · 2016 to 2025
$4.8M
Validation of an automated acoustic outcome measure for AdLDF32DC020349 · NIDCD · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI MARKS, KATHERINE LINDSEY · 2022 to 2023
$142k
NIDCD NIH HHS F32 DC020349NIDCD NIH HHS L30 DC020598NIDCD NIH HHS R01 DC015570
6 · The paper itself

Abstract

objectiveAdductor laryngeal dystonia (AdLD) is a neurological disorder characterized by spasms of the laryngeal muscles during speech, resulting in acoustic discontinuities. High-speed videoendoscopy (HSV) has been used to capture supraglottic compression and visual obstructions of the vocal folds during sustained phonation in speakers with AdLD. The purpose of this study was to investigate the co-occurrence of these laryngeal postures via HSV and acoustic discontinuities in speakers with and without AdLD during connected speech.

methodsSpeakers with (n = 16) and without (n = 16) AdLD read sentences while undergoing trans nasal laryngoscopy. Microphone and HSV signals were simultaneously recorded. Acoustic discontinuities and laryngeal postures via HSV were independently manually labeled. A multinomial logistic regression was performed to examine the relationship between the presence of acoustic discontinuities-labeled as phonatory break, creak, or frequency shift-and that of view of vocal fold obstruction and supraglottic compression. Additional fixed factors included in the regression model were group (AdLD, control), sex, and the interactions of group × obstruction and group × supraglottic compression.

resultsFactors that were significantly associated with the odds of an acoustic discontinuity included group, vocal fold obstruction, supraglottic compression, and the interaction of group × vocal fold obstruction. There was not a significant interaction effect of group on supraglottic compression events.

conclusionsThese findings suggest that acoustic discontinuities co-occur with supraglottic compression and vocal fold obstructions. Understanding this relationship may lead to more effective voice assessment methods for individuals with AdLD.

Indexed as

DystoniaLaryngeal DiseasesLaryngeal MusclesLaryngoscopyAdultAgedFemaleHumansLarynxMaleMiddle AgedPhonationPostureVideo RecordingVocal Cordsdystonialaryngoscopyspasmspeechvocal cords

Identifiers

PMID41320962
PMCPMC12671927

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.