GABA

Mariana Brizuela, Anuja R Bony, Sonia Garcia-Caraballo, David J Adams, Stuart M Brierley

Abstract read

In one paragraph

Article in Experimental physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

GABAExperimental physiology · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mariana BrizuelaVisceral Pain Research Group, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, South Australia, Australia.

Anuja R BonyMolecular Horizons/Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, New South Wales, Australia.

Sonia Garcia-CaraballoVisceral Pain Research Group, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, South Australia, Australia.

David J AdamsMolecular Horizons/Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, New South Wales, Australia.ORCID https://orcid.org/0000-0002-7030-2288

Stuart M BrierleyVisceral Pain Research Group, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, South Australia, Australia.ORCID https://orcid.org/0000-0002-2527-2905

Funding

National Health and Medical Research Council (NHMRC) of Australia Investigator Leadership APP2008727NHMRC APP1072113NSW Health Cardiovascular Disease Senior Researcher

6 · The paper itself

Abstract

Chronic visceral pain is a key symptom of irritable bowel syndrome. Modulation of voltage-gated calcium and potassium channels by G protein-coupled receptors plays a key role in dampening nociceptive transmission. Both baclofen and the analgesic peptide α-conotoxin Vc1.1 activate GABA

Indexed as

Calcium Channels, N-TypeG Protein-Coupled Inwardly-Rectifying Potassium ChannelsHyperpolarization-Activated Cyclic Nucleotide-Gated ChannelsNociceptionReceptors, GABA-BSensory Receptor CellsAnimalsBaclofenColonConotoxinsFemaleGanglia, SpinalHumansMaleMiceMice, Inbred C57BLBaclofenCalcium Channels, N-TypeConotoxinsG Protein-Coupled Inwardly-Rectifying Potassium ChannelsHyperpolarization-Activated Cyclic Nucleotide-Gated ChannelsReceptors, GABA-Banalgesic peptidebaclofencolonic afferentsdorsal root gangliaelectrophysiologyion channelneuronal excitability

Identifiers

PMID41320901

DOI10.1113/EP093318

PMCPMC13140288

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.