Trial reportJournal of the International Society of Sports Nutrition2025
Amino acid supplementation accelerates resolution of exercise-induced phagocyte infiltration in human skeletal muscle.
Trial report in Journal of the International Society of Sports Nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Ginsenoside Rg1 enhances stem cell abundance in aging human skeletal muscle after resistance exercise.Journal of ginseng research · 2026Article
- Damage-induced muscle regeneration after exercise in humans: Modulatory effects of ginsenoside Rg1.Journal of traditional and complementary medicine · 2026Review
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAmino acids activate neutrophil phagocytosis and free radical release
aimWe examined the effects of amino acid supplementation on post-exercise accumulation of myeloperoxidase-positive (MPO⁺) cells in human skeletal muscle using a randomized, double-blind, placebo-controlled crossover design.
methodsTen young men (22 ± 2.8 years) consumed either amino acids (15 g) or an isocaloric placebo before resistance exercise. Biopsies of the vastus lateralis muscle were collected at baseline, immediately after exercise (0 h), and 24 h post-exercise.
resultsResistance exercise increased MPO⁺ cell infiltration (+161%,
conclusionThese findings indicate that amino acid supplementation accelerates the resolution of inflammation in exercised human skeletal muscle. Immunofluorescence evidence further suggests that infiltrating bone marrow-derived cells contribute to fast mitochondrial gains as part of the muscle damage-response following exercise.
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