ArticleChemistry & biodiversity2026
Phytochemical Profiling, Molecular Docking, and ER Stress-Mediated Apoptosis Induced by Plantago loeflingii L. Essential Oil in Ovarian Adenocarcinoma Cells.
Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Plantago loeflingii L. (Plantaginaceae) is traditionally used for wound healing and tumor treatment, yet its cellular effects remain unexplored. This study provides the first integrated evaluation of its essential oil (PLA-EO), including chemical composition, cytotoxicity, mechanistic assays, and molecular docking. Hydrodistillation followed by GC-MS/GC-FID identified 53 constituents (98.33%), dominated by linalool (23.81%), palmitic acid (15.34%), limonene (10.54%), thymol (8.51%), and α-terpineol (5.23%). PLA-EO selectively inhibited ovarian adenocarcinoma BG-1 cells (IC
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