ArticleOral diseases2026
Temporomandibular Joint Osteoarthritis Modeling Methods' Efficacy in SD Rats: A Scoping Review.
Article in Oral diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
objectivesThis scoping review aimed to evaluate the efficacy of different temporomandibular joint osteoarthritis (TMJOA) modeling methods in inducing condylar cartilage degeneration and subchondral bone loss in SD rats. MATERIALS AND
methodsPubMed, Embase, and Web of Science databases were searched for animal studies that established TMJOA models in SD rats and reported histological or micro-CT evaluation parameters. Two reviewers examined the methods and results sections of each selected study, performed methodological quality assessments, and extracted data.
resultsFifty-seven studies met the eligibility criteria and were selected for analysis. The majority of these studies were rated as having a high risk of bias across the assessed domains. Three categories of TMJOA modeling methods (intra-articular injection, excessive mechanical loading, surgery) comprising fourteen specific techniques were identified and their data were analyzed.
conclusionsAt the early time, disc perforation could effectively induce subchondral bone loss, while monosodium iodoacetate (MIA) injection, over mandibular advancement, mandibular deviation, occlusal elevation, and excessive mouth opening could effectively damage both condylar cartilage and subchondral bone. At the long time, partial discectomy could effectively promote condylar cartilage degeneration, while MIA injection, unilateral anterior crossbite, and posterior occlusal disorder could effectively induce condylar cartilage degradation and subchondral bone loss.
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Registered trials
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