Evidence map›Paper›PMID 41318790›Full record

ArticleScientific reports2025

Isolation of bacteria that catabolize abiotically synthesized tetroses via the formose reaction.

Kosei Kawasaki, Kensuke Igarashi, Hiro Tabata, Hiroaki Nishijima, Shuji Nakanishi, Souichiro Kato

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Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kosei KawasakiBiomanufacturing Process Research Center, National Institute of Advanced Industrial Science and Technology, 2-17-2-1, Tsukisamu-Higashi, Toyohira, Sapporo, 062-8517, Japan.
Kensuke IgarashiBiomanufacturing Process Research Center, National Institute of Advanced Industrial Science and Technology, 2-17-2-1, Tsukisamu-Higashi, Toyohira, Sapporo, 062-8517, Japan.
Hiro TabataResearch Center for Solar Energy Chemistry, Graduate School of Engineering Science, The University of Osaka, 1-3 Machikaneyama, Toyonaka, Osaka, 560-8531, Japan.
Hiroaki NishijimaResearch Center for Solar Energy Chemistry, Graduate School of Engineering Science, The University of Osaka, 1-3 Machikaneyama, Toyonaka, Osaka, 560-8531, Japan.
Shuji NakanishiResearch Center for Solar Energy Chemistry, Graduate School of Engineering Science, The University of Osaka, 1-3 Machikaneyama, Toyonaka, Osaka, 560-8531, Japan.
Souichiro KatoBiomanufacturing Process Research Center, National Institute of Advanced Industrial Science and Technology, 2-17-2-1, Tsukisamu-Higashi, Toyohira, Sapporo, 062-8517, Japan. sou-kato@g.ecc.u-tokyo.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sugars synthesized through abiotic processes, specifically the formose reaction, are promising candidates for next-generation feedstocks for biomanufacturing. One of the significant challenges associated with the utilization of abiotically synthesized sugars via the formose reaction is the presence of unusual sugars, which are not metabolized by typical microorganisms. This study aimed to identify microorganisms capable of catabolizing tetroses, which are among the unusual sugars present in the abiotically synthesized sugars. Tetroses were not catabolized by and exhibited inhibitory effects on model bacteria commonly used in biomanufacturing. We isolated eight phylogenetically diverse bacterial strains capable of catabolizing and tolerating tetroses. The isolates exhibited the ability to grow in high concentrations of the abiotically synthesized sugars, which inhibit the growth of typical microorganisms, and to consume tetroses contained therein. Further investigation into the molecular mechanisms of tetrose metabolisms in the isolates will facilitate the development of biomanufacturing processes utilizing the abiotically synthesized sugars.

Indexed as

BacteriaPhylogeny

Identifiers

PMID41318790
PMCPMC12780249

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.