Evidence map›Paper›PMID 41318759›Full record

ArticleScientific reports2025

Synthesis and insecticidal activity of some pyrazole, pyridine, and pyrimidine candidates against Culex pipiens L. larvae.

Eman A E El-Helw, Eman A El-Bordany, Doaa R Abdel-Haleem, Sara F El-Fagal, Eman A Ghareeb

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Eman A E El-HelwChemistry Department, Faculty of Science, Ain Shams University, Cairo, 11566, Egypt.
Eman A El-BordanyChemistry Department, Faculty of Science, Ain Shams University, Cairo, 11566, Egypt.
Doaa R Abdel-HaleemEntomology Department, Faculty of Science, Ain Shams University, Cairo, 11566, Egypt.
Sara F El-FagalChemistry Department, Faculty of Science, Ain Shams University, Cairo, 11566, Egypt.
Eman A GhareebChemistry Department, Faculty of Science, Ain Shams University, Cairo, 11566, Egypt. emanghareeb@sci.asu.edu.eg.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The expansion of the Culex pipiens population has increased the spread of arboviruses, due to the ineffectiveness of several traditional insecticides available to control this vector. Some heterocycles bearing a benzoquinoline moiety, such as pyrazoline, pyridine, pyridone, and pyrimidine derivatives, were synthesized from the reaction of 3-(3-chlorobenzo[f]quinolin-2-yl)-1-(4-chlorophenyl)prop-2-en-1-one with some nitrogen and carbon nucleophiles. The synthesized compounds were investigated against laboratory and field strains of C. pipiens larvae. The activities of prepared derivatives were varied, where compounds 7, 5, and 9 showed good toxicities with LC

Indexed as

CulexInsecticidesPyrazolesPyridinesPyrimidinesAnimalsLarvaStructure-Activity RelationshipInsecticidesPyrazolespyridinePyridinespyrimidinePyrimidinesBenzo[f]quinolinesCulex pipiensInsecticidal activityPyrazolinesResistance level

Identifiers

PMID41318759
PMCPMC12672691

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.