Evidence map›Paper›PMID 41318741›Full record

ArticleScientific reports2025

Exploring artificial intelligence chatbots in pediatric fluoride education: a cross-sectional study.

Nevra Karamüftüoğlu, Ezgi Aydın Varol, Cenkhan Bal

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nevra KaramüftüoğluDepartment of Pediatric Dentistry, Gülhane Faculty of Dentistry, University of Health Sciences, Ankara, 06010, Turkey. nvrserbest@hotmail.com.ORCID http://orcid.org/0000-0002-5045-5551
Ezgi Aydın Varol, Ankara, Turkey.
Cenkhan BalDepartment of Pediatric Dentistry, Gülhane Faculty of Dentistry, University of Health Sciences, Ankara, 06010, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Large language model-based (LLM) chatbots are increasingly integrated into healthcare communication, offering accessible and interactive information. These artificial intelligence (AI) tools have the potential to influence caregiver health behaviors when tailored to user needs and literacy levels. In pediatric dentistry, fluoride remains a cornerstone of caries prevention but is also subject to public concerns and online misinformation, underscoring the need for reliable digital communication. This observational and exploratory study evaluated the performance of three advanced AI chatbots-ChatGPT-4.o, Google Gemini Pro, and DeepSeek V3-in providing fluoride-related information to parents and caregivers in the context of pediatric oral health. Twenty fluoride-related questions, derived from American Academy of Pediatric Dentistry (AAPD) guideline themes, were presented to each chatbot in standardized sessions. Responses were independently evaluated by three blinded reviewers using validated tools: EQIP, DISCERN, Global Quality Scale (GQS), Flesch Reading Ease Score (FRES), Flesch-Kincaid Reading Grade Level (FKRGL), and iThenticate similarity index. These instruments assessed quality, reliability, readability, and originality. Inter-rater reliability was confirmed with intraclass correlation coefficients (ICCs). Statistical analyses were conducted using ANOVA or Kruskal-Wallis tests with appropriate post-hoc methods. ChatGPT-4.o achieved significantly higher EQIP (M = 4.32, SD = 0.43) and DISCERN (M = 4.20, SD = 0.48) scores than Gemini Pro and DeepSeek V3 (p < 0.001), indicating superior reliability and informational quality. While FRES (median = 68.5, p = 0.12) and Similarity Index (≤ 10%, p = 0.54) showed no significant differences, ChatGPT consistently produced more readable and original content. FKRGL differences were borderline (p = 0.041) but not retained after correction, and GQS outcomes were comparable. These findings suggest that ChatGPT's superior performance is not only statistically significant but also practically relevant for enhancing parental comprehension of fluoride use. Among the evaluated models, ChatGPT-4.o demonstrated the clearest and most reliable fluoride communication. Its higher EQIP and DISCERN scores highlight its potential as a supportive tool for caregiver education in pediatric dentistry. Nonetheless, these systems should be implemented cautiously, complemented with professional oversight, and continuously validated to prevent misinformation and ensure safe clinical integration.

Indexed as

Artificial IntelligenceFluoridesCaregiversChildCross-Sectional StudiesFemaleGenerative Artificial IntelligenceHumansMaleOral HealthParentsFluoridesArtificial intelligenceChatbotsFluoridePediatric dentistry

Identifiers

PMID41318741
PMCPMC12764934

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.