ArticleNature communications2025
A thermo-electroreduction strategy unlocks propylene glycol synthesis from glycerol at ampere level current density.
Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
The production of valuable chemicals from glycerol can alleviate its large market surplus and reduce emissions that arise from petrochemical-based feedstocks. Here we show that a thermo-electroreduction strategy can expand the scope of glycerol valorization to a product of higher effective H/C ratio, such as propylene glycol. The thermal dehydration of glycerol unlocks the hydroxyacetone intermediate, which can undergo subsequent electrocatalytic hydrogenation to propylene glycol using Co-cluster-decorated Cu foam electrocatalyst. Theoretical simulations suggest that Co/Cu modulates the adsorption configuration of hydroxyacetone, such that all functional groups are in similar distance from the surrounding water layer and the surface. This can facilitate low-energy-barrier hydrogenation of the O atom on hydroxyacetone by solvated H species through an Eley-Rideal-type mechanism, followed by spontaneous hydrogenation of the adjacent C atom. We thus achieve high Faradaic efficiencies towards propylene glycol of ~81% even at current densities up to 1000 mA/cm
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.