Evidence map›Paper›PMID 41318520›Full record

ArticleAIDS research and therapy2025

Exploring multilevel barriers and facilitators to antiretroviral therapy adherence among adults living with HIV in ART clinic in Mogadishu, Somalia: a qualitative study guided by the socio-ecological model.

Mohamed Jayte, Abdifitah Abdullahi Mohamed, Abdifatah Karshe, Farah Dubad Abdi, Fathi Ali Araye, Ahmed Shafie Adan

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Article in AIDS research and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1 · What the graph read from it

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1 citing paper in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Mohamed JayteDepartment of Internal Medicine, Kampala International University, P.O. Box 7062, Kampala, Uganda. maxamedjeyte@gmail.com.
Abdifitah Abdullahi MohamedDepartment of Microbiology, Kampala International University, Kampala, Uganda.
Abdifatah KarsheDepartment of Internal Medicine, Kampala International University, P.O. Box 7062, Kampala, Uganda.
Farah Dubad AbdiDepartment of Internal Medicine, Kampala International University, P.O. Box 7062, Kampala, Uganda.
Fathi Ali ArayeDepartment of Psychiatric and Mental Health, Kampala International University, Kampala, Uganda.
Ahmed Shafie AdanDepartment of Cardiology at Somali Türkiye Training and Research, Mogadishu, Somalia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAntiretroviral therapy (ART) has dramatically reduced HIV-related morbidity and mortality worldwide, but adherence remains a critical challenge, particularly in Sub-Saharan Africa. In Somalia, where HIV prevalence is low but health systems are fragile, little is known about the lived experiences of people living with HIV (PLHIV) regarding ART adherence.

methodsA qualitative study was conducted at ART clinic In Mogadishu Somalia between March-August 2024. A total of 22 adult PLHIV and 12 healthcare providers (8 ART nurses and 4 case managers) participated. Purposive sampling was used to recruit participants; Data were collected through 30 in-depth interviews and 4 focus group discussions using semi-structured guides. Interviews were audio-recorded, transcribed, translated, and thematically analyzed using NVivo software, with emerging themes classified into barriers and facilitators of adherence.

resultsBarriers to adherence included stigma and discrimination, religious and cultural beliefs (such as reliance on prayer or holy water), economic hardship (transport costs, food insecurity), health system challenges (stock-outs, long waiting times, confidentiality concerns), and psychological factors (depression, denial). Facilitators included strong family and social support, religious coping that motivated adherence, positive patient-provider relationships, peer support networks, and personal motivation and resilience, particularly among patients committed to living for their children. Illustrative quotes highlighted the daily struggles and strategies patients employed to remain in care.

conclusionART adherence in Somalia is shaped by complex interactions between socio-cultural, economic, psychological, and health system factors. Interventions that reduce stigma, integrate mental health services, strengthen health systems, provide economic and food support, and leverage religious and peer networks are essential. Collaborating with traditional and religious leaders may further improve acceptance and sustainability of ART programs.

Indexed as

Anti-HIV AgentsAnti-Retroviral AgentsHIV InfectionsMedication AdherenceAdultFemaleFocus GroupsHumansMaleMiddle AgedQualitative ResearchSocial StigmaSomaliaAnti-HIV AgentsAnti-Retroviral AgentsAdherenceAntiretroviral therapyBarriersFacilitatorsHIVQualitative studySomaliaStigma

Identifiers

PMID41318520
PMCPMC12772106

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