Evidence map›Paper›PMID 41318513›Full record

ArticleBMC psychology2025

Changes in life decisions and in emotions following genetic testing for cancer risk.

Ilaria Durosini, Giulia Ongaro, Serena Oliveri, Valeria Sebri, Gabriella Pravettoni

Abstract read
In one paragraph

Article in BMC psychology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ilaria DurosiniDepartment of Oncology and Hemato-Oncology, University of Milan, Milan, Italy. ilaria.durosini@unimi.it.
Giulia OngaroApplied Research Division for Cognitive and Psychological Science, IEO, European Institute of Oncology IRCCS, Milan, Italy.
Serena Oliveri"Aldo Ravelli" Center for Neurotechnology and Brain Therapeutics, Department of HealthSciences, DISS, University of Milan, Milan, Italy.
Valeria SebriApplied Research Division for Cognitive and Psychological Science, IEO, European Institute of Oncology IRCCS, Milan, Italy.
Gabriella PravettoniDepartment of Oncology and Hemato-Oncology, University of Milan, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genetic testing is essential for understanding the onset of advanced cancer. Women who tested positive for a BRCA1/2 pathogenic variant experience changes in their everyday life, affecting their emotions, behaviors, and social relationships due to their “at risk” status. Moreover, a new sense of urgency arises when planning future decisions. This study aims to explore the psychological experiences of women who have undergone genetic testing through a qualitative thematic analysis. Nine Italian women who received BRCA1/2 risk information participated in this study. Semi-structured interviews were conducted by expert psycho-oncologists. All the data were collected online via a web conferencing platform, using both video and audio. Interviews explored two areas: the first focused on emotional changes following the genetic testing results and the second is focused on the changes in daily life and personal decisions. In the first area, two themes related to negative and positive emotions and their related eight sub-themes emerged. In the second area, two main themes related to personal and social changes, which were further divided into five sub-themes, were identified. Future studies could explore how to better address emotional and behavioral challenges faced by BRCA1/2 carriers, by providing adequate psychological support and improving doctor-patient communication.

Indexed as

Breast NeoplasmsDecision MakingEmotionsGenetic Predisposition to DiseaseGenetic TestingAdultFemaleGenes, BRCA1Genes, BRCA2HumansMiddle AgedQualitative ResearchBRCA mutationCancerCancer screeningDecision-makingEmotionsGenetic testing

Identifiers

PMID41318513
PMCPMC12801691

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.