Observational studyBMC oral health2025
Management of molar-incisor hypomineralisation (MIH) with CAD/CAM indirect hybrid composite restorations in children: a retrospective observational case series.
Observational study in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Clinical performance of glass hybrid and short fiber-reinforced composite restorations in MIH-affected molars: A 60-month split-mouth randomized controlled trial.Clinical oral investigations · 2026Trial
- Clinical comparison of CAD/CAM nanohybrid composite and hybrid ceramic overlays in children with molar-incisor hypomineralisation: a split-mouth prospective randomized clinical trial.Clinical oral investigations · 2026Trial
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background/purposeThis retrospective observational case series aimed to evaluate the clinical and digital (photographic) success rate of CAD/CAM hybrid composite indirect restorations used on molar- incisor hypomineralisation affected first permanent molars (FPMs) after 12 months." MATERIALS AND
methodsA total ofnine children (mean age: 11.62 ± 1.26 years) with MIH- affected FPMs (receiving a score of 2c or 4c according to the MIH-TNI classification) received 13 CAD/CAM indirect hybrid composite restorations. Restorations were assessed after a follow-up period of twelve months. Anatomic form, marginal adaptation, marginal discoloration, color match, surface texture, restoration fracture, and secondary caries were assessed both clinically and digitally through intraoral photographs, according to modified United States Public Health Service criteria. Descriptive and exploratory analyse were conducted, including the McNemar Chi-square test. The significance level used in the statistical analysis (p < 0.05).
resultsThe survival rate of the restorations was 100% after 12 months. According to the USPHS evaluation criteria, the majority of restorations were scored as Alpha. Specifically, for color match, 10 restorations (77%) were rated Alpha and 3 (23%) as Bravo at the 12-month evaluation. The difference in color match scores between baseline and 12 months was statistically significant (p= 0.025). For marginal discoloration, scores decreased from 100% Alpha at baseline to 12 (92%) Alpha and 1 (8%) Bravo at the 12-month follow-up. A statistically significant difference was also found between baseline and 12-month scores for marginal discoloration (p = 0.025).
conclusionThe findings highlight the potential of CAD/CAM restorations as a reliable treatment option for MIH-affected FPMs, particularly in cases with severe structural compromise. However, these results need to be confirmed through long-term randomized controlled clinical trials with larger cohorts, double-blinded protocols, and longer follow-up periods.
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Registered trials
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