Evidence map›Paper›PMID 41317270›Full record

GuidelineClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2026

SEOM-GEICAM-SOLTI clinical guidelines for early-stage breast cancer (UPDATE 2025).

Francisco Ayala de la Peña, Silvia Antolín Novoa, Joaquín Gavilá Gregori, Lucía González Cortijo, Fernando Henao Carrasco, María Teresa Martínez Martínez, Cristina Morales Estévez, Agostina Stradella, María Jesús Vidal Losada, Eva Ciruelos

Abstract readPractice Guideline
In one paragraph

Guideline in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Francisco Ayala de la PeñaDepartment of Medical Oncology, Hospital General Universitario Gregorio Marañón, Hospital Oncológico y de Terapias Avanzadas, Calle Maiquez 7, 28007, Madrid, Spain. frayala@ucm.es.ORCID http://orcid.org/0000-0001-6311-920X
Silvia Antolín NovoaDepartment of Medical Oncology, Complexo Hospitalario Universitario, A Coruña (CHUAC), Coruña, Spain.
Joaquín Gavilá GregoriFundación Instituto Valenciano de Oncología (IVO), Valencia, Spain.
Lucía González CortijoMedical Oncology Department, Hospital Universitario Quirónsalud, Madrid, Spain.
Fernando Henao CarrascoHospital Universitario Virgen Macarena, Seville, Spain.
María Teresa Martínez MartínezMedical Oncology Department, INCLIVA Biomedical Research Institute, Hospital Clínico of Valencia, University of Valencia, Valencia, Spain.
Cristina Morales EstévezHospital Universitario Reina Sofía, Córdoba, Spain.
Agostina StradellaMedical Oncology Department, Institut Català d'OncologiaL'Hospitalet, Barcelona, Spain.
María Jesús Vidal LosadaHospital Clínic, Barcelona, Spain.
Eva CiruelosMedical Oncology Department, Breast Cancer Unit, University Hospital 12 de Octubre, Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer is the leading cause of cancer in women in Spain and its annual incidence is rapidly increasing. As a result of the screening programs in place, nearly 90% of breast cancer cases are detected in early and potentially curable stages. In recent years, locoregional and systemic therapies have increasingly been directed by new diagnostic tools that have improved the balance between toxicity and clinical benefit. New therapeutic strategies, such as immunotherapy, targeted drugs, and antibody-drug conjugates, have also improved outcomes in some patient subgroups. This clinical practice guideline for early-stage breast cancer (updated in 2025) is based on a systematic review of relevant studies and on the consensus of experts from the Spanish Breast Cancer Research Group (GEICAM), Spanish Collaborative Group for the Study, Treatment and Other Experimental Strategies in Solid Tumors (SOLTI), and Spanish Society of Medical Oncology (SEOM).

Indexed as

Breast NeoplasmsFemaleHumansMedical OncologyNeoplasm StagingSpainAdjuvantEarly breast cancerFollow-upNeoadjuvant

Identifiers

PMID41317270
PMCPMC12790541

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.