Evidence map›Paper›PMID 41317215›Full record

ArticleMolecular neurobiology2025

Neuroprotective Role of Piperine-Encapsulated Casein Micelles in Mitigating Intracellular Dyshomeostasis in Alzheimer's Disease Pathology.

Jayapriya Mishra, Charan Singh, Jasvinder Singh Bhatti

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Piperine: From Green Extraction to Clinical Translation-A Review.Drug design, development and therapy · 2026
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jayapriya MishraDepartment of Human Genetics and Molecular Medicine, School of Health Sciences, Central University of Punjab, Bathinda, Punjab, 151401, India.
Charan SinghDepartment of Pharmaceutical Sciences, H.N.B. Garhwal University, Srinagar, Garhwal, 246174, Uttarakhand, India. c.singhniper09@gmail.com.
Jasvinder Singh BhattiDepartment of Human Genetics and Molecular Medicine, School of Health Sciences, Central University of Punjab, Bathinda, Punjab, 151401, India. jasvinder.bhatti@cup.edu.in.

Funding

DST-INSPIRE Fellowship IF4190498Science and Engineering Research Board EEQ/ 2020/000188
6 · The paper itself

Abstract

Alzheimer's disease remains a complex neurodegenerative disorder characterized by multifactorial mechanisms that undermine the efficacy of monotherapeutic strategies. Multi-targeted therapies have emerged as promising strategies, particularly those addressing mitochondrial dysfunction, a key contributor to AD pathophysiology. This study explores the neuroprotective efficacy of piperine encapsulated casein micelles (PIP@CMs) against Aβ

Indexed as

AlkaloidsAlzheimer DiseaseBenzodioxolesCaseinsHomeostasisIntracellular SpaceMicellesNeuroprotective AgentsPiperidinesPolyunsaturated AlkamidesAmyloid beta-PeptidesCell Line, TumorCell SurvivalHumansMembrane Potential, MitochondrialMitochondriaAlkaloidsAmyloid beta-PeptidesBenzodioxolesCaseinsMicellesNeuroprotective AgentsPeptide FragmentsPiperidinespiperinePolyunsaturated AlkamidesReactive Oxygen SpeciesAlzheimer’s diseaseMitochondria homeostasisNano-micellesNeurotoxicityOxidative stressPiperine

Identifiers

PMID41317215

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.