ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025
Haematopoietic stem cell transplantation for children and young people: is there a role for prehabilitation? A scoping review.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Trimodal prehabilitation for hematopoietic stem cell transplantation: A best evidence summary.Asia-Pacific journal of oncology nursing · 2026Review
- Article
- Caregiver's Kitchen: A Mixed Methods Feasibility Study of a Culinary Medicine and Coaching Intervention for Caregivers of Children With Cancer.Integrative cancer therapiesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
purposePrehabilitation interventions show positive outcomes for adults undergoing haematopoietic stem cell transplantation (HSCT). Their impact on paediatric populations is less clear. This scoping review describes current prehabilitation literature, intervention feasibility, and effectiveness in improving health outcomes for children following HSCT.
methodsFollowing the Joanna Briggs Institute methodology, a comprehensive search of databases (AHMED, CINAHL, Cochrane library, EMCARE, MEDLINE, PsycINFO, PubMed) and grey literature was conducted. Key search terms included "HSCT", "prehabilitation" (physical functioning, nutritional status, health behaviours), "children/young people" and "health outcomes". Data related to review aims was extracted.
resultsFrom 134 studies, nine met inclusion criteria (three (33%) on physical functioning, six (67%) examined nutritional status, 0 health behaviours). Eight (89%) were retrospective, with one prospective providing baseline data from a RCT. Pre-HSCT muscle strength, endurance, balance, and quality of life are lower than age-matched peers. Higher pre-HSCT muscle strength (hip flexion p = 0.002) and physical function (10 m walk p = 0.004, time-to-rise-from-floor p < 0.001) correlate with improved post-HSCT recovery. Underweight (p-values 0.035-0.044) and overweight status (p-values 0.0021-0.0413) are associated with adverse clinical outcomes. Feasibility of assessment is demonstrated with no adverse events recorded.
conclusionInitial results are promising, with a clear need for pre-HSCT assessment in clinical settings; however, no conclusions on the effectiveness of prehabilitation can be drawn. Findings emphasise the need for further research, supporting grant applications for intervention protocols.
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Registered trials
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