Evidence map›Paper›PMID 41317164›Full record

ArticleJACC. Case reports2026

Unintentional Septal Arterial Entry During Left Bundle Branch Area Pacing.

Jacopo Costantino, Barbara Romani, Lorenzo Maria Zuccaro, Massimiliano Campoli, Daniele Porcelli

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jacopo CostantinoDepartment of Cardiology, Ospedale San Pietro Fatebenefratelli, Rome, Italy; Department of Clinical, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy; Department of Medicine, University of Padova, Padova, Italy. Electronic address: jacopo.costantino@uniroma1.it.
Barbara RomaniDepartment of Cardiology, Ospedale San Pietro Fatebenefratelli, Rome, Italy.
Lorenzo Maria ZuccaroDepartment of Cardiology, Ospedale San Pietro Fatebenefratelli, Rome, Italy.
Massimiliano CampoliDepartment of Cardiology, Ospedale San Pietro Fatebenefratelli, Rome, Italy.
Daniele PorcelliDepartment of Cardiology, Ospedale San Pietro Fatebenefratelli, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLeft bundle branch area pacing (LBBAP) is increasingly adopted as a physiological pacing strategy. Deep septal lead deployment, however, may occasionally result in unexpected vascular staining. CASE SUMMARY: A 70-year-old woman with advanced atrioventricular block and preserved ejection fraction underwent LBBAP. During contrast injection to assess septal lead depth, unexpected opacification of the left anterior descending artery and a septal perforator branch occurred, suggesting inadvertent vascular entry. The lead was promptly repositioned more proximally, achieving optimal electrical parameters. The patient remained asymptomatic, and follow-up echocardiography confirmed preserved ventricular function without pericardial effusion or hematoma. DISCUSSION: To our knowledge, this is the first report providing direct angiographic visualization of coronary opacification during LBBAP, highlighting the importance of septal vascular anatomy and imaging guidance. TAKE-HOME MESSAGES: Inadvertent vascular staining during LBBAP is rare and usually benign when promptly recognized. Angiographic contrast injection is useful to confirm lead position and detect unintended vascular entry.

Indexed as

leadleft bundle branch area pacingpacemakervascular staining

Identifiers

PMID41317164
PMCPMC12926318

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.