Evidence map›Paper›PMID 41317131›Full record

ArticleInternational forum of allergy & rhinology2026

Eosinophil Peroxidase as a Dynamic Indicator of Treatment Response in Eosinophilic Chronic Rhinosinusitis.

Jacquelyn K Callander, Annabelle R Charbit, Camryn Marshall, Kritika Khanna, Steven D Pletcher, Jose G Gurrola, Andrew H Murr, Monica Tang, Andrew N Goldberg, Patricia A Loftus

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International forum of allergy & rhinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jacquelyn K CallanderDepartment of Otolaryngology-Head and Neck Surgery, Stanford University, Stanford, California, USA.
Annabelle R CharbitCardiovascular Research Institute, University of California, San Francisco, California, USA.
Camryn MarshallDepartment of Otolaryngology-Head and Neck Surgery, University of California, San Francisco, California, USA.
Kritika KhannaCardiovascular Research Institute, University of California, San Francisco, California, USA.
Steven D PletcherDepartment of Otolaryngology-Head and Neck Surgery, University of California, San Francisco, California, USA.ORCID https://orcid.org/0000-0003-0127-927X
Jose G GurrolaDepartment of Otolaryngology-Head and Neck Surgery, University of California, San Francisco, California, USA.ORCID https://orcid.org/0000-0001-6801-5768
Andrew H MurrDepartment of Otolaryngology-Head and Neck Surgery, University of California, San Francisco, California, USA.
Monica TangDivision of Pulmonary, Critical Care, Allergy and Sleep and the Department of Medicine, University of California, San Francisco, California, USA.
Andrew N GoldbergDepartment of Otolaryngology-Head and Neck Surgery, University of California, San Francisco, California, USA.
Patricia A LoftusDepartment of Otolaryngology-Head and Neck Surgery, University of California, San Francisco, California, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

key pointsEosinophil peroxidase (EPX) correlates with local type 2 inflammation and may serve as a noninvasive biomarker of eosinophilic chronic rhinosinusitis. EPX declines after surgery and dupilumab, highlighting its potential to track treatment response. High baseline EPX predicts patients likely to achieve a clinically meaningful Sinonasal Outcome Test-22 change.

Indexed as

EosinophiliaEosinophil PeroxidaseRhinitisSinusitisAntibodies, Monoclonal, HumanizedBiomarkersChronic DiseaseEosinophilsHumansMaleRhinosinusitisTreatment OutcomeAntibodies, Monoclonal, HumanizedBiomarkersdupilumabEosinophil Peroxidasebiomarkerchronic rhinosinusitiscytokineendotypeeosinophil peroxidasenasal polyptype 2 inflammation

Identifiers

PMID41317131
PMCPMC12761348

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.