Evidence map›Paper›PMID 41316985›Full record

Trial reportClinical gerontologist

A Pilot Trial for Midlife and Older Adults: Sleep and Circadian Treatment Plus Memory Support and Boosters.

Laurel D Sarfan, Anne E Milner, Joshua Varghese, Estephania Ovalle Patino, Heather E Hilmoe Yates, Vera Portnova, Marlen Diaz, Emma R Agnew, Catherine A Callaway, Krista Fisher and 4 more

Abstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Clinical gerontologist. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Laurel D SarfanUniversity of California, Berkeley, Berkeley, California, USA.
Anne E MilnerUniversity of California, Berkeley, Berkeley, California, USA.
Joshua VargheseUniversity of California, Berkeley, Berkeley, California, USA.
Estephania Ovalle PatinoUniversity of California, Berkeley, Berkeley, California, USA.
Heather E Hilmoe YatesUniversity of California, Berkeley, Berkeley, California, USA.
Vera PortnovaUniversity of California, Berkeley, Berkeley, California, USA.
Marlen DiazUniversity of California, Berkeley, Berkeley, California, USA.
Emma R AgnewUniversity of California, Berkeley, Berkeley, California, USA.
Catherine A CallawayUniversity of California, Berkeley, Berkeley, California, USA.
Krista FisherUniversity of California, Berkeley, Berkeley, California, USA.
Garret ZieveUniversity of California, Berkeley, Berkeley, California, USA.
Caitlin GasperettiUniversity of California, Berkeley, Berkeley, California, USA.
Sondra S TiabUniversity of California, Berkeley, Berkeley, California, USA.
Allison G HarveyUniversity of California, Berkeley, Berkeley, California, USA.

Funding

Implementing and Sustaining a Transdiagnostic Sleep and Circadian Treatment to Improve Severe Mental Illness Outcomes in Community Mental Health.R01MH120147 · NIMH · UNIVERSITY OF CALIFORNIA BERKELEY · PI HARVEY, ALLISON G · 2019 to 2023
$3.9M
Improving sleep and circadian functioning, daytime functioning, and well-being for midlife and older adults by improving patient memory for a transdiagnostic sleep and circadian treatmentR01AG082651 · NIA · UNIVERSITY OF CALIFORNIA BERKELEY · PI Allison G Harvey · 2023 to 2026
$2.5M
Advancing Sustainability of Evidence-Based Treatments in Community Mental HealthF32MH131284 · NIMH · UNIVERSITY OF CALIFORNIA BERKELEY · PI SARFAN, LAUREL D · 2022 to 2024
$76k
NIA NIH HHS R01 AG082651NIMH NIH HHS F32 MH131284NIMH NIH HHS R01 MH120147
6 · The paper itself

Abstract

objectivesSleep and circadian problems are prevalent among midlife and older adults. Unfortunately, treatments for these problems are limited by poor memory for treatment.

methodsWe conducted a pilot trial of the Transdiagnostic Intervention for Sleep and Circadian Dysfunction paired with the Memory Support Intervention (TSC+MSI) for midlife and older adults with sleep and circadian problems (

resultsFollowing TSC+MSI, patients significantly improved on sleep disruption, sleep-related impairment, functional impairment, and select sleep diary outcomes. Therapist use of memory support strategies moderated improvements in sleep-related and overall impairment. TSC+MSI was perceived as acceptable by patients and feasible by therapists. Most patients opted in to the boosters. Sleep-related impairment significantly improved from pre-booster to post-booster.

conclusionsFollowing TSC+MSI and boosters, improvements were observed in clinical outcomes, and signals supported feasibility and acceptability. CLINICAL IMPLICATIONS: Although comparisons with control conditions and larger samples are needed, TSC+MSI and booster messages may improve sleep and circadian and related outcomes among midlife and older adults.

Indexed as

Memory DisordersSleep Wake DisordersAgedFemaleHumansMaleMemoryMiddle AgedPilot ProjectsSleepTreatment OutcomeBoostersinsomniamemory supportmidlifeoldersleeptransdiagnostic treatment

Identifiers

PMID41316985
PMCPMC12700498

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.