SynthesisJournal of cosmetic dermatology2025
Optimizing Collagen Biostimulator Choice in LATAM: Expert Consensus on Patient Selection, Ethnic Skin Phenotypes, and Accessibility.
Synthesis in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Optimizing Collagen Biostimulator Choice in LATAM: Expert Consensus on Patient Selection, Ethnic Skin Phenotypes, and Accessibility.Journal of cosmetic dermatology · 2025Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe diverse ethnic skin phenotypes and socioeconomic landscape of Latin America (LATAM) necessitate tailored approaches to collagen biostimulators, calcium hydroxylapatite (CaHA) and poly-l-lactic acid (PLLA). A region-specific consensus on their optimal use is lacking.
objectivesTo establish expert consensus guidelines on patient selection, techniques, and practical application of CaHA and PLLA for collagen biostimulation in LATAM populations.
methodsA modified Delphi process was conducted with 14 LATAM experts. Following a systematic literature review, 58 statements were drafted across key clinical domains. Consensus was defined as ≥ 75% agreement, stratified as strong (≥ 85%) or moderate (75%-84%).
resultsStrong consensus was achieved on 51 statements (87.9%), with 4 reaching moderate consensus. Key recommendations include: selecting CaHA for thicker skin and immediate volumization, and PLLA for thinner skin and long-term collagen remodeling; using specific dilution protocols (e.g., CaHA 1:1 for face, 1:4 for body); employing cannulas for safety; and implementing vigorous post-PLLA massage. Initial disagreements on age-based restrictions were resolved through literature review, achieving final consensus.
conclusionThis consensus provides the first LATAM-specific framework for CaHA and PLLA use, integrating ethnic diversity, anatomical considerations, and accessibility to optimize safety and efficacy in regenerative aesthetics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.