Evidence map›Paper›PMID 41316731›Full record

ArticleJournal of applied clinical medical physics2025

Clinical application of 3D-printed bolus in postmastectomy radiotherapy.

Qianqian Liu, Xuming Chen, Zhekai Hu, Lingtong Hou, Yihang Zhang, Tiening Zhang, Shengyu Yao

Abstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Clinical application of 3D-printed bolus in postmastectomy radiotherapy.Journal of applied clinical medical physics · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qianqian LiuDepartment of Radiation Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, P. R. China.
Xuming ChenDepartment of Radiation Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, P. R. China.
Zhekai HuDepartment of Radiation Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, P. R. China.
Lingtong HouDepartment of Radiation Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, P. R. China.
Yihang ZhangDepartment of Radiation Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, P. R. China.ORCID https://orcid.org/0009-0007-1314-8070
Tiening ZhangDepartment of Radiation Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, P. R. China.
Shengyu YaoDepartment of Radiation Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, P. R. China.ORCID https://orcid.org/0000-0001-5388-0636

Funding

Shanghai Association of Chinese Integrative Medicine YG202308Shanghai Key Laboratory of Molecular Imaging 18DZ2260400Shanghai Songjiang Science and Technology Commission 2023SJKJGG048
6 · The paper itself

Abstract

purposeTo evaluate the fitting accuracy and dose influence of 3D-printed bolus (3DPB) during postmastectomy radiotherapy.

methodsAir gaps were assessed using cone-beam computed tomography (CBCT) images for 27 breast cancer patients who received postmastectomy radiotherapy. Then a CIRS thoracic phantom was used to evaluate the dosimetric effects of different air gap sizes.

resultsIn CBCT images of patients, compared with conventional bolus (CB), 3DPB significantly reduced both the maximum and total air gap volumes by an average between 103.04 cm

conclusionsFor breast cancer radiotherapy patients immobilized using a vacuum bag, as evidenced by the CBCT images and phantom simulation, 3DPB provides a superior anatomical fit, reducing air gaps and associated dose loss in postmastectomy radiotherapy. When the air gap height ≤ 2 cm, dose attenuation with CB remains clinically acceptable, suggesting that 3D printing may not be necessary unless the skin in the gap area is at high risk for recurrence. However, for gaps > 2 cm, the dose reduction becomes significant, warranting the use of 3D-printed boluses to ensure adequate target coverage.

Indexed as

Breast NeoplasmsCone-Beam Computed TomographyMastectomyPhantoms, ImagingPrinting, Three-DimensionalRadiotherapy Planning, Computer-AssistedFemaleHumansMiddle AgedOrgans at RiskRadiotherapy DosageRadiotherapy, Intensity-Modulated3D‐printed bolusAir gapPostmastectomyRadiation therapy

Identifiers

PMID41316731
PMCPMC12662813

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.