Evidence map›Paper›PMID 41316524›Full record

ArticlePhysiological reports2025

Microvascular arteriolar reactivity in response to skeletal muscle contractions in female and male hamsters.

Nicole M Fletcher, Coral L Murrant

Abstract read
In one paragraph

Article in Physiological reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nicole M FletcherDepartment of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada.
Coral L MurrantDepartment of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada.ORCID 0000-0003-4196-7181

Funding

Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada (NSERC) RGPIN-2019-05146
6 · The paper itself

Abstract

Microvascular control mechanisms involved in the blood flow response to muscle contractions have been well documented in males but remain poorly understood in females. Therefore, we characterized arteriolar vasodilation in situ using intravital microscopy of the retractor muscle of anesthetized female and male hamsters (8-13 weeks). Arterioles were stimulated physiologically by contracting 3-5 skeletal muscle fibers overlying the arteriole for 2 min using a range of twitch and tetanic stimulation parameters: 6, 15, and 60 contractions per minute (cpm) at 20 Hz, or 4, 20, and 70 Hz at 15 cpm (250 ms train duration) and pharmacologically via 2 min micropipette application of nitric oxide (NO, 10

Indexed as

Muscle ContractionMuscle, SkeletalVasodilationAcetylcholineAdenosineAnimalsArteriolesCricetinaeFemaleMaleMesocricetusNitric OxideVasodilator AgentsAcetylcholineAdenosineNitric OxideVasodilator Agentsactive hyperaemiaarteriolemuscle contractionskeletal musclevasodilation

Identifiers

PMID41316524
PMCPMC12662791

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.