Evidence map›Paper›PMID 41316504›Full record

ArticleJournal of health, population, and nutrition2025

Low-dose radiation exposure and health outcomes among healthcare workers: a multi-center prospective cohort study.

Xiaobin Liu, Qian Su, Jing Zhang, Yan Chen, Fei Li, Caixia Xie, Li He, Shiyu Liu, Yu Lv

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of health, population, and nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xiaobin Liu *Public Health Department, School of Medicine, Sichuan Academy of Medical Sciences, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, No. 32, West Section 2, 1 st Ring Road, Chengdu, 610072, China.
Qian Su *Health Management Center, School of Medicine, Sichuan Academy of Medical Sciences, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, 610072, China.
Jing Zhang *Laboratory Center, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, 610020, China.
Yan ChenOccupational and Radiological Supervision Law Enforcement Detachment, Sichuan Province Health and Family Planning Supervision and Law Enforcement Corps, Chengdu, 610020, China.
Fei LiPublic Health Department, School of Medicine, Sichuan Academy of Medical Sciences, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, No. 32, West Section 2, 1 st Ring Road, Chengdu, 610072, China.
Caixia XieDepartment of Nursing, School of Medicine, Sichuan Academy of Medical Sciences, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, 610072, China.
Li HePublic Health Department, Sichuan Provincial People's Hospital Pujiang Hospital, Chengdu, 611630, China.
Shiyu LiuPublic Health Department, School of Medicine, Sichuan Academy of Medical Sciences, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, No. 32, West Section 2, 1 st Ring Road, Chengdu, 610072, China. lsyaaa@126.com.
Yu LvPublic Health Department, School of Medicine, Sichuan Academy of Medical Sciences, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, No. 32, West Section 2, 1 st Ring Road, Chengdu, 610072, China. 29381636@qq.com.

Funding

Science and Technology Department of Sichuan Province 2023NSFSC0534
6 · The paper itself

Abstract

backgroundThe long-term effects of chronic low-dose radiation exposure remain a subject of debate, with studies suggesting a range of outcomes from negligible to significant health impacts.

methodsThis multi-center cohort study followed 210 newly hired healthcare workers in radiation-related occupations for 9 years, from January 2015 to December 2023. Health effects were evaluated using Repeated Measures Analysis of Variance (rMANOVA). Significant interactions were explored using Bonferroni's post hoc analysis and Bayesian methods. Repeated-measures regression models and Restricted Cubic Splines (RCS) models were employed to further assess the statistical significance and strength of evidence. Sensitivity analyses were performed employing Generalized Estimating Equations (GEE) to ensure robustness of the results.

resultsThe per-protocol set included 111 subjects after accounting for exclusions and losses to follow-up. The rMANOVA models identified subtle but statistically significant differences across multiple follow-up intervals for various health indices. Parameters with Bayes factors (BF

conclusionsThis pioneering longitudinal cohort study in western China demonstrates that chronic low-dose radiation exposure among healthcare workers can induce subtle yet significant health effects, underscoring the necessity of adhering to the ALARA principle for radiation exposure management.

Indexed as

Health PersonnelOccupational ExposureRadiation ExposureAdultBayes TheoremCohort StudiesFemaleHumansMaleMiddle AgedProspective StudiesRadiation DosageHealthcare radiation workers.Health effectsPersonal dose equivalent

Identifiers

PMID41316504
PMCPMC12661757

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.