Evidence map›Paper›PMID 41316496›Full record

SynthesisSystematic reviews2025

The role of physical activity and exercise in gynecologic cancer care: protocol for an umbrella review.

Porawan Witwaranukool, Kathryn Kynoch, Ritin Fernandez

Abstract readSystematic Review
In one paragraph

Synthesis in Systematic reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Porawan WitwaranukoolRamathibodi School of Nursing, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand. Porawanwitwaranukool@gmail.com.ORCID 0000-0001-6901-6965
Kathryn KynochMater Health and JBI Queensland Centre for Evidence-Based Health Innovation, Brisbane, Australia.
Ritin FernandezSchool of Nursing and Midwifery, University of Newcastle, Newcastle, NSW, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGynecologic cancers are associated with long-term physical and psychological challenges. Physical activity (PA) and exercise are increasingly recognized as important components of cancer care. However, no umbrella review has synthesized evidence across gynecologic cancers. This review aims to evaluate the effectiveness of PA and exercise in improving health outcomes.

methodsThis umbrella review will include systematic reviews and meta-analyses assessing the impact of PA and exercise on physical and psychological outcomes. Searches will be conducted in MEDLINE, CINAHL, Embase, ProQuest Health and Medical Collection, Scopus, Web of Science, Thai Journal Online (ThaiJO), and gray literature. Two reviewers will independently screen, extract data, and assess methodological quality using the Joanna Briggs Institute (JBI) critical appraisal tool. Overlap of primary studies will be quantified using the Graphical Representation of Overlap for OVErviews (GROOVE) method. Findings will be synthesized narratively and summarized using two approaches: (1) a traffic light system will be used to visually indicate the effectiveness of each intervention (green = benefit, orange = no effect or inconclusive, red = harm or lower effectiveness) and (2) the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) framework will be applied to rate the certainty of evidence for each intervention-outcome as high, moderate, low, or very low. DISCUSSION: This review will provide the first comprehensive synthesis of PA and exercise interventions in gynecologic cancers, generating evidence-based recommendations to guide tailored survivorship care. SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42024548933.

Indexed as

ExerciseExercise TherapyGenital Neoplasms, FemaleFemaleHumansSystematic Reviews as TopicExerciseGynecologic cancerPhysical activityUmbrella review protocol

Identifiers

PMID41316496
PMCPMC12661806

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.