Evidence map›Paper›PMID 41316368›Full record

ArticleJournal of neuroengineering and rehabilitation2025

Corticomuscular coupling study for post-stroke rehabilitation: a scoping review.

Shuai Feng, Xianxian Yu, Yinfan Guo, Bohui Zheng, Jiaojiao Peng, Pu Wang, Wanqing Wu

Abstract readScoping Review
In one paragraph

Article in Journal of neuroengineering and rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shuai Feng *School of Biomedical Engineering, Sun Yat-sen University, Shenzhen, 518107, Guangdong, China.
Xianxian Yu *Department of Rehabilitation Medicine, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, Guangdong, China.
Yinfan GuoSchool of Biomedical Engineering, Sun Yat-sen University, Shenzhen, 518107, Guangdong, China.
Bohui ZhengDepartment of Rehabilitation Medicine, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, Guangdong, China.
Jiaojiao PengDepartment of Rehabilitation Medicine, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, Guangdong, China.
Pu WangDepartment of Rehabilitation Medicine, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, Guangdong, China. wangp288@mail.sysu.edu.cn.
Wanqing WuSchool of Biomedical Engineering, Sun Yat-sen University, Shenzhen, 518107, Guangdong, China. wuwanqing@mail.sysu.edu.cn.

Funding

National Key Research and Development Program of China No. SQ2023YFE0100690National Natural Science Foundation of China, Joint Fund Project U21A20479Shenzhen Municipal Science, Technology and Innovation Commission, Basic Research General Program JCYJ20240813150250045Shenzhen Municipal Science, Technology and Innovation Commission, Major Science and Technology Project KJZD20230923115114028Sun Yat-sen University, Clinical Medicine 5010 Special Program 2024010
6 · The paper itself

Abstract

The challenge of post-stroke rehabilitation lies in the difficulty of quantifying the dynamic process of neural remodeling using traditional assessment methods. Corticomuscular coupling (CMC), as an emerging neurophysiological index, offers a novel perspective for quantifying this dynamic process of neural remodeling following a stroke and optimizing rehabilitation interventions. This paper systematically reviews the research advancements in CMC within stroke rehabilitation through a scoping review, focusing on four primary areas: mechanisms, analytical methods, experimental paradigms, and interventions. Studies indicate that CMC can assess the neural mechanisms underlying motor dysfunction and guide personalized rehabilitation strategies by analyzing the dynamic information transfer between the brain and muscles. However, current studies encounter challenges such as technical calibration difficulties, insufficient sample sizes, and the heterogeneity of experimental paradigms. Moving forward, it is essential to promote large-sample multicenter studies, standardize the analytical processes, and explore the synergistic application of CMC with brain-computer interfaces and other technologies to facilitate the paradigm shift from experience-driven to data-driven stroke rehabilitation.

Indexed as

Motor CortexMuscle, SkeletalStrokeStroke RehabilitationBrain-Computer InterfacesElectromyographyHumansCorticomuscular CouplingNeuromodulationRehabilitation AssessmentRehabilitation InterventionStroke

Identifiers

PMID41316368
PMCPMC12764111

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.