Evidence map›Paper›PMID 41316240›Full record

ArticleMalaria journal2025

Knowledge, attitude and practice in high endemic settings for malaria: a cross-sectional study in a rural community in central Mozambique.

Joaquim Domingos Lequechane, Falume Chale, Nicole Azevedo, Ana Paula Abílio, Alberto Gabriel Muanido, Luzia Gonçalves, João Luís Manuel, Henrique Silveira

Registry-linked trialAbstract read
In one paragraph

Article in Malaria journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04419766 (Evaluation of IR3535 as a Spatial Repellent for Malaria Control.), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04419766 naactive not recruitingnot on this map

Evaluation of IR3535 as a Spatial Repellent for Malaria Control. (Avaliação da eficácia do Repelente Ambiental 3-(N-acetyl-n-butyl) Aminopropionic Acid Ethyl Ester (IR3535) Como Ferramenta Para o Controlo da malária).

TypeinterventionalSponsorUniversidade Nova de LisboaRan2021 to 2025Enrolled166ConditionsMalariaArmsIR3535 (3-(N-acetyl-N-butyl) aminopropionic acid ethyl ester) house spraying
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Joaquim Domingos LequechaneGlobal Health and Tropical Medicine (GHTM), Associate Laboratory in Translation and Innovation Towards Global Health (LA-REAL), Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa (IHMT-NOVA), Rua da Junqueira 100, 1349-008, Lisbon, Portugal. Joaquim.lequechane@ins.gov.mz.
Falume ChaleCentro de Investigação Operacional da Beira (CIOB), Instituto Nacional de Saúde, Ministério da Saúde, Rua Correia de Brito 1323, Ponta Gêa, Cidade da Beira, Mozambique.
Nicole AzevedoFundação Belmiro de Azevedo, Praça de Liège, 146, 4150-455, Porto, Portugal.
Ana Paula AbílioInstituto Nacional de Saúde de Moçambique, Vila de Marracuene, Maputo, Mozambique.
Alberto Gabriel MuanidoComité Para Saúde de Moçambique (CSM), Beira, Mozambique.
Luzia GonçalvesCentro de Estatística E Aplicações da Universidade de Lisboa (CEAUL), Campo Grande, Lisbon, Portugal.
João Luís ManuelCentro de Investigação Operacional da Beira (CIOB), Instituto Nacional de Saúde, Ministério da Saúde, Rua Correia de Brito 1323, Ponta Gêa, Cidade da Beira, Mozambique.
Henrique SilveiraGlobal Health and Tropical Medicine (GHTM), Associate Laboratory in Translation and Innovation Towards Global Health (LA-REAL), Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa (IHMT-NOVA), Rua da Junqueira 100, 1349-008, Lisbon, Portugal. HSilveira@ihmt.unl.pt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMalaria remains a public health threat globally, mainly in African countries. Despite the progress made over the years, its control and elimination by 2030 appear to be a challenge. The community perspective on factors contributing to malaria burden is essential to develop preventive measures adapted to local contexts. Understanding the transmission rates, symptoms, prevention and treatment of malaria are essential for a population to effectively control the disease. This study assessed the knowledge, attitude, and practice (KAP) of Tambai residents to identify the possible gaps related to high malaria burden in a study implementation area.

methodsThis was a cross-sectional study design with a qualitative approach held in Sofala province, Nhamatanda district, Tambai community. This KAP study was carried out before the intervention in May 2021 and after in June 2022. All heads of households from the study implementation area were surveyed using a semi-structured questionnaire. Data were processed in Microsoft excel, exported and analysed in Statistical Packages for the Social Sciences (SPSS) version 29.0.

resultsThe knowledge of the heads of households on symptoms, mode of transmission, prevention and treatment of malaria was high before and after the intervention (149; 96.8%) and (143; 91.1%), respectively. Heads of households show no differences on KAP regarding symptoms, mode of transmission, prevention and treatment of malaria when intervention and control or before and after intervention were compared.

conclusionBoth intervention and control groups showed high KAP before and after intervention, suggesting that the implementation of the REPELMALARIA project did not have an either positive nor negative impact on KAP scores. These findings suggests that the higher malaria cases in the study area are not related to the malaria knowledge, attitude and practice of householders.

trial registrationThis results are from the main clinical trial registed in ClinicalTrials.gov ID: NCT04419766.

Indexed as

Endemic DiseasesHealth Knowledge, Attitudes, PracticeMalariaRural PopulationAdolescentAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedMozambiqueRandomized Controlled Trials as TopicYoung AdultAttitudeKnowledgeMalariaMozambiquePracticeSpatial repellent

Identifiers

PMID41316240
PMCPMC12664178

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.