Evidence map›Paper›PMID 41316216›Full record

ArticleBMC public health2025

HIV/AIDS epidemiological profile and intervention evaluation of rural elderly in China.

Xiaoyi Zhou, Yuyu Zhang, Ping Zhu, Zixiao Zhou, Jianfei Gao, Yiyao Song, Qiwei Ge, Anni Chen, Xuan Shi, Kai Liu and 4 more

Abstract read
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Xiaoyi Zhou *Institute for Applied Research in Public Health, School of Public Health, Nantong University, Nantong, China.
Yuyu Zhang *School of Public Health, Nantong University, No.9 Seyuan Road, Nantong, 226019, China.
Ping Zhu *Department of STD and AIDS Control and Prevention, Nantong Center for Disease Control and Prevention, Nantong, China.
Zixiao ZhouFaculty of Medical and Health, The University of Sydney, Sydney, Australia.
Jianfei GaoDepartment of Infectious Diseases Control and Prevention, Rudong Center for Disease Control and Prevention, Nantong, China.
Yiyao SongDepartment of Infectious Diseases Control and Prevention, Rudong Center for Disease Control and Prevention, Nantong, China.
Qiwei GeSchool of Public Health, Nantong University, No.9 Seyuan Road, Nantong, 226019, China.
Anni ChenSchool of Public Health, Nantong University, No.9 Seyuan Road, Nantong, 226019, China.
Xuan ShiSchool of Public Health, Nantong University, No.9 Seyuan Road, Nantong, 226019, China.
Kai LiuDepartment of STD and AIDS Control and Prevention, Nantong Center for Disease Control and Prevention, Nantong, China.
Shijing ZhangDepartment of STD and AIDS Control and Prevention, Nantong Center for Disease Control and Prevention, Nantong, China.
Meiyin ZouThe Third people's hospital of Nantong, Nantong, China.
Congxia WuThe Third people's hospital of Nantong, Nantong, China.
Xun ZhuangInstitute for Applied Research in Public Health, School of Public Health, Nantong University, Nantong, China. xzhuang@ntu.edu.cn.

Funding

the Clinical medicine special project in Nantong university 2022JZ009the Graduate Research & Practice Innovation Program of Jiangsu Province KYCX23_3435the Graduate Research & Practice Innovation Program of Jiangsu Province KYCX25_3826the Nantong Municipal Health Commission Project MB2021075the Nantong Municipal Health Commission Project MS2023077the Nantong Natural Science Foundation and Social and People's Livelihood Science and Technology Plan Project MSZ2023129the National Key R& D Program 2022YFC2304901the Preventive Medicine Research Project of Jiangsu Provincial Health Commission Ym2023079
6 · The paper itself

Abstract

introductionHIV infection among older adults in rural China has risen significantly in recent years, yet epidemiological characteristics and intervention effectiveness remain understudied.

methodsWe described the characteristics of 179 HIV/AIDS patients aged ≥ 50 years in rural Nantong, China, then conducted a community-based 1:1 case-control study of 179 HIV/AIDS patients aged ≥ 50 years and developed a predictive nomogram. Mediation analysis was applied to explore the role of HIV knowledge, and the effectiveness of a comprehensive community intervention was assessed among 1206 community individuals.

resultsThere were 179 elderly HIV/AIDS participants recruited, 55.9% of them were homosexual transmission, and 84.4% were identified through passive pathways. The case-control showed that the protective factors associated with HIV infection included higher Perceived Social Support Score (PSSS) (OR = 0.023) and knowledge awareness (OR = 0.055), while the risk factors included being unemployed (OR = 4.852), having extramarital sex (OR = 30.264), and the tolerant attitude to extramarital sex (OR = 7.124). The C-index is 0.9 and the Dxy is 0.913 with Spiegelhalter Z-test, indicating that the nomogram has good predictive accuracy. Mediation analysis indicated that knowledge mediated the impact of PSSS, extramarital sex, and attitude towards extramarital sex on HIV infection, accounting for 30.8%, 26.6% and 14.1%of the effects, respectively. Six months after implementation of the comprehensive intervention, there was a significant increase in HIV knowledge awareness (from 41.0% to 84.4%) and a decrease in extramarital sex(from 2.4% to 0.8%).

conclusionAppropriate interventions for the rural elderly with low education can also effectively reduce AIDS related risky behaviors. PSSS can be considered as a potential screening factor to predict the risk of HIV infection.

Indexed as

Health Knowledge, Attitudes, PracticeHIV InfectionsRural PopulationAgedCase-Control StudiesChinaFemaleHumansMaleMiddle AgedNomogramsRisk FactorsSocial SupportCase-controlElderlyEpidemiologyHIV/AIDSInterventionRural

Identifiers

PMID41316216
PMCPMC12763857

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.