ArticleBMC surgery2025
Clinical outcomes after laparoscopic left hemihepatectomy with and without biliary duct exploration.
Article in BMC surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundThe operative procedures of laparoscopic left hemihepatectomy (LLH) with and without common bile duct (CBD) exploration are largely different. However, the two procedures are frequently included in the same category. The present study aimed to evaluate the impact of CBD exploration on clinical outcome in patients undergoing LLH, especially postoperative liver function and biliary leakage.
methodsThe retrospective study included patients with left-sided intrahepatic bile duct stones at the First Affiliated Hospital of Nanchang University from January 2020 to June 2024. Patients were divided into simple LLH group and LLH with CBD exploration (LLHCBDE) group. Perioperative outcomes and stone recurrence between the two groups were evaluated. Moreover, we performed multivariable linear regression to analyze peak postoperative levels of alanine transaminase (ALT) and aspartate transaminase (AST) and logistic regression to analyze the occurrence of biliary leakage.
resultsThis study enrolled 176 patients, with 36 and 140 patients in the LLH and LLHCBDE groups, respectively. The LLHCBDE group demonstrated significantly longer operation time, longer hospital stays, higher peak postoperative transaminase levels, and a higher stone recurrence rate compared to the LLH group. However, there were no significant differences in the peak postoperative values of t-Bil and PT-INR, incidence of major complications or biliary leakage between the two groups. Multivariate stepwise linear regression analysis revealed that CBD exploration was an independent predictor of peak postoperative levels of alanine transaminase (β = 0.313, P < 0.001) and aspartate transaminase (β = 0.359, P < 0.001). Furthermore, period of less than 1 month between LLH and the latest episode of acute cholangitis (OR 4.362, 95%CI 1.126-16.904, P = 0.033) and intraoperative blood loss (OR 1.022, 95%CI 1.013-1.031, P < 0.001) were independent risk factors for postoperative biliary leakage.
conclusionsDespite conferring a distinct clinical profile characterized by slower recovery, a higher rate of stone recurrence and higher peak postoperative transaminase levels, the addition of CBD exploration to LLH did not impair functional hepatic regeneration or increase the risk of biliary leakage.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.