Evidence map›Paper›PMID 41316196›Full record

Observational studyAIDS research and therapy2025

Effectiveness of B/F/TAF in adults with HIV who are viremic with M184V/I.

Charlotte-Paige Rolle, Michelle L D'Antoni, Roberto Corales, Andrea Marongiu, Joshua Gruber, Tanya Schreibman, Dionne Bell, Chiu-Bin Hsiao, Indira Brar

Abstract readObservational Study
In one paragraph

Observational study in AIDS research and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Charlotte-Paige RolleOrlando Immunology Center, Orlando, FL, USA.
Michelle L D'AntoniGilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA, 94404, USA. michelle.dantonibrogan@gilead.com.ORCID 0009-0004-5395-7022
Roberto CoralesGilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA, 94404, USA.
Andrea MarongiuGilead Sciences Europe Ltd, Uxbridge, UK.
Joshua GruberGilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA, 94404, USA.
Tanya SchreibmanCAN Community Health, Sarasota, FL, USA.
Dionne BellCapitol City Family Health Center, Baton Rouge, LA, USA.
Chiu-Bin HsiaoPositive Health Clinic, Allegheny Health Network, Pittsburgh, PA, USA.
Indira BrarHenry Ford Health System, Detroit, MI, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF) is indicated for people with HIV who are virologically suppressed, including those with M184V/I. Data on B/F/TAF effectiveness during viremia with M184V/I are limited. This observational study retrospectively collected clinical/demographic data from adults with viremia and M184V/I receiving B/F/TAF or alternate antiretroviral therapy (ART). Virologic suppression at 3 and ≥ 6 months was evaluated. For participants with data, 5/5 (100%) and 7/8 (88%) on B/F/TAF and 4/6 (67%) and 7/10 (70%) on alternate ART achieved virologic suppression at 3 and ≥ 6 months, respectively. Virologic suppression was achieved in most people with HIV who were viremic with M184V/I on B/F/TAF, as with alternate ART.

Indexed as

AdenineAnti-HIV AgentsHIV-1HIV InfectionsTenofovirViremiaAdultAlanineAmidesDrug Resistance, ViralEmtricitabineFemaleHeterocyclic Compounds, 3-RingHumansMaleMiddle AgedAdenineAlanineAmidesAnti-HIV AgentsbictegravirEmtricitabineHeterocyclic Compounds, 3-RingPiperazinesPyridonesTenofovirtenofovir alafenamideEffectiveness of B/F/TAFM184V/IViremia

Identifiers

PMID41316196
PMCPMC12661699

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.