ArticleBiomedical engineering online2025
Effects of cardiac decellularized extracellular matrix hydrogel as a functional myocardial patch on the growth of cardiomyocytes.
Article in Biomedical engineering online, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Article
- Injectable bioactive hydrogels as pharmacological drug delivery platforms for post-myocardial infarction cardiac repair: therapeutic cargo engineering, stimuli-responsive release mechanisms, and translational perspectives.Naunyn-Schmiedeberg's archives of pharmacology · 2026Review
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2 authors.
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Abstract
objectivesTo address the immune rejection and inflammatory reactions that currently exist in functional myocardial patches when promoting myocardial cell growth.
methodsThe cardiac acellular Decellularized Extracellular Matrix (dECM) hydrogel was prepared and used as a functional myocardial patch for immune rejection and inflammatory reaction.
resultsCompared with hyaluronic acid hydrogel and cardiomyocytes in tissue culture plate, the cardiomyocytes in the cardiac dECM hydrogel had the strongest cell viability. After 5 days of culture, the cell viability increased to 292.9% relative to control. Moreover, after the hydrogel culture, the relative expression levels of CACNA1C and ATP2A2 genes in cardiomyocytes reached 3.43 and 1.83, respectively, which were also higher than those in the other two groups.
conclusionsFrom the above results, cardiac dECM hydrogel can promote the growth of cardiomyocytes.
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