Evidence map›Paper›PMID 41316136›Full record

ArticleBMC public health2025

Social integration and mortality across the life course: findings from the Tromsø study.

Ainhoa Ugarteche Pérez, Nadine El Rashidi, Erlend Hoftun Farbu, Raphaële Castagné, Sameline Grimsgaard, Tom Wilsgaard, Dragana Vuckovic, David Tang, Marc Chadeau-Hyam, Torkjel M Sandanger and 3 more

Abstract read
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In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ainhoa Ugarteche PérezEQUITY research team, Inserm, CERPOP-UMR1295, Université Toulouse III Paul Sabatier, 37 Allées Jules Guesde, Toulouse, 31000, France. ainhoa.ugarteche-perez@inserm.fr.
Nadine El RashidiEQUITY research team, Inserm, CERPOP-UMR1295, Université Toulouse III Paul Sabatier, 37 Allées Jules Guesde, Toulouse, 31000, France.
Erlend Hoftun FarbuDepartment of Community Medicine, Faculty of Health Sciences, UiT the Arctic University of Norway, Tromsø, Norway.
Raphaële CastagnéEQUITY research team, Inserm, CERPOP-UMR1295, Université Toulouse III Paul Sabatier, 37 Allées Jules Guesde, Toulouse, 31000, France.
Sameline GrimsgaardDepartment of Community Medicine, Faculty of Health Sciences, UiT the Arctic University of Norway, Tromsø, Norway.
Tom WilsgaardDepartment of Community Medicine, Faculty of Health Sciences, UiT the Arctic University of Norway, Tromsø, Norway.
Dragana VuckovicDepartment of Epidemiology and Biostatistics, School of Public Health, Faculty of Medicine, Imperial College London, London, UK.
David TangDepartment of Epidemiology and Biostatistics, School of Public Health, Faculty of Medicine, Imperial College London, London, UK.
Marc Chadeau-HyamDepartment of Epidemiology and Biostatistics, School of Public Health, Faculty of Medicine, Imperial College London, London, UK.
Torkjel M SandangerDepartment of Community Medicine, Faculty of Health Sciences, UiT the Arctic University of Norway, Tromsø, Norway.
Cyrille DelpierreEQUITY research team, Inserm, CERPOP-UMR1295, Université Toulouse III Paul Sabatier, 37 Allées Jules Guesde, Toulouse, 31000, France.
Michelle Kelly-IrvingEQUITY research team, Inserm, CERPOP-UMR1295, Université Toulouse III Paul Sabatier, 37 Allées Jules Guesde, Toulouse, 31000, France.
Lola NeufcourtEQUITY research team, Inserm, CERPOP-UMR1295, Université Toulouse III Paul Sabatier, 37 Allées Jules Guesde, Toulouse, 31000, France.

Funding

Norges Forskningsråd 289440
6 · The paper itself

Abstract

contextPoor social relationships have been associated with increased mortality risk. Configurations of social relationships vary across the life course, affecting the association with mortality. We investigated the relationship between social integration and mortality in four age groups and to examine three blocks of potential intermediate variables.

methodsTromsø Study wave 4 and 6 data and mortality events in the Norwegian Population Registry were linked. A three-level (low, medium, high) social integration index (SII) was constructed from scores to three related items: social participation, living with spouse and frequency of contact with friends. Adjusted cox-regression models and including intermediate variables in blocks (1:behavioral, 2:psychosocial resources, 3:biological markers) were conducted in the study population (N = 9879) and in age-stratified subsamples: [25-52]y. (N = 6785); [53-59]y. (N = 1679); [60-65]y. (N = 846); [66-74]y. (N = 569). Additional sex-stratified and causes-of-death models (cancer, cardiovascular diseases, neuropsychiatric conditions and other deaths) were constructed.

resultsA graded SII and mortality risk association was observed in confounder-adjusted models in the total study population: individuals with medium and low SII had incrementally higher risk of mortality compared to those with high SII (HR

conclusionOur study consolidates evidence on the relationship between social integration and mortality risk, especially in mid-adulthood, and suggests some potential underlying pathways. To reduce mortality risk inequalities, we encourage structurally addressing social marginalization.

Indexed as

MortalitySocial IntegrationAdultAgedCause of DeathFemaleHumansMaleMiddle AgedNorwayRegistriesLife-courseMortalitySocial relations

Identifiers

PMID41316136
PMCPMC12661694

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.